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Condition (MeSH)

Periprosthetic Fractures

ClinicalTrials.gov lists 12 trials for Periprosthetic Fractures or a narrower condition beneath it.

MeSH D057068 Wounds and Injuries C26
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Phase 4 Phase 4 1 Not applicable Not applicable 1 Observational Observational 10 Phase 4 Phase 4 1 Not applicable Not applicable 1 Observational Observational 10

Trials per phase

12 of the 12 trials are tagged with Periprosthetic Fractures itself; the rest are tagged with a narrower condition beneath it.

Get the Periprosthetic Fractures report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Periprosthetic Fractures trials start? (9)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 4
  • Not applicable
  • Observational

Top of scale: 2

2000: 1 trials (Observational 1) 2012: 1 trials (Phase 4 1) 2014: 2 trials (Observational 1, Not applicable 1) 2016: 1 trials (Observational 1) 2018: 2 trials (Observational 2) 2019: 1 trials (Observational 1) 2021: 1 trials (Observational 1) 2024: 2 trials (Observational 2) 2025: 1 trials (Observational 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 1
2024 2
2021 1
2019 1
2018 2
2016 1
2014 2
2012 1
2000 1

No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 12 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Periprosthetic Fractures trials in? (3)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 4 1
Not applicable 1
Observational 10

How many Periprosthetic Fractures trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 4
Active, not recruiting 1
Completed 3
Terminated 1
Unknown status 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Periprosthetic Fractures trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
41medical AG 1
Maxx Orthopedics Inc 1
TIPMED Medical Device Manufacturing Ltd. Co. 1

Interventions as named in the registry (2)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Bisphosphonates, Combinations 1
Not applicable- observational study 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Periprosthetic Fractures? (66)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Internal fixation versus revision arthroplasty for Vancouver B2-B3 fractures: mortality and functional outcomes in frail patients. Insights from the PIPPAS study of 485 patients. Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 2025 Yes
Unexpected Positive Cultures in Hip and Knee Periprosthetic Fractures. The Journal of arthroplasty 2024 Yes
Optimizing periprosthetic fracture management and in-hospital outcome: insights from the PIPPAS multicentric study of 1387 cases in Spain. Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 2024 Yes
Periprosthetic Femoral Fractures-Beyond B2. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews 2024 Yes
Primary total knee arthroplasty in tibial plateau fractures: Literature review and our institutional experience. Injury 2023 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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