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Condition (MeSH)

Vitelliform Macular Dystrophy

ClinicalTrials.gov lists 10 trials for Vitelliform Macular Dystrophy or a narrower condition beneath it. National Eye Institute (NEI) has the most among industry and government lead sponsors, with 2.

MeSH D057826 Eye Diseases C11 C16
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Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 1 Observational Observational 7 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 1 Observational Observational 7

Trials per phase

10 of the 10 trials are tagged with Vitelliform Macular Dystrophy itself; the rest are tagged with a narrower condition beneath it.

Get the Vitelliform Macular Dystrophy report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Vitelliform Macular Dystrophy trials start? (7)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1/2
  • Phase 2
  • Observational

Top of scale: 3

2007: 1 trials (Phase 1/2 1) 2011: 1 trials (Observational 1) 2014: 3 trials (Observational 2, Phase 2 1) 2021: 2 trials (Observational 2) 2024: 1 trials (Observational 1) 2025: 1 trials (Phase 1/2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 1
2024 1
2021 2
2014 3
2011 1
2007 1

No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Vitelliform Macular Dystrophy trials in? (3)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1/2 2
Phase 2 1
Observational 7

How many Vitelliform Macular Dystrophy trials are recruiting? (4)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 5
Completed 3
Unknown status 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Vitelliform Macular Dystrophy trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Eye Institute (NEI) 2
Opus Genetics, Inc 1

Which drugs are being tested for Vitelliform Macular Dystrophy? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
SILDENAFIL 1

Interventions as named in the registry (1)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
ranibizumab PRN 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Vitelliform Macular Dystrophy? (1)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Treatment of Macular Degeneration with Sildenafil: Results of a Two-Year Trial. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 2018 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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