Skip to content
Pharma Observatory a Scientist.com platform

Condition (MeSH)

Peri-Implantitis

ClinicalTrials.gov lists 318 trials for Peri-Implantitis or a narrower condition beneath it.

MeSH D057873 Stomatognathic Diseases C07
Email me this page as a PDF

Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 4 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 7 Phase 4 Phase 4 17 Not applicable Not applicable 167 Observational Observational 118 Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 4 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 7 Phase 4 Phase 4 17 Not applicable Not applicable 167 Observational Observational 118

Trials per phase (log scale)

318 of the 318 trials are tagged with Peri-Implantitis itself; the rest are tagged with a narrower condition beneath it.

Get the Peri-Implantitis report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Peri-Implantitis trials start? (21)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 34

2000: 1 trials (Observational 1) 2007: 1 trials (Phase 1/2 1) 2008: 2 trials (Phase 4 1, Phase 3 1) 2009: 2 trials (Observational 1, Not applicable 1) 2010: 6 trials (Observational 1, Not applicable 3, Phase 3 1, Phase 2 1) 2011: 2 trials (Observational 1, Phase 2 1) 2012: 7 trials (Observational 2, Not applicable 2, Phase 4 1, Phase 3 2) 2013: 11 trials (Observational 3, Not applicable 3, Phase 4 3, Phase 2/3 1, Phase 2 1) 2014: 12 trials (Observational 2, Not applicable 7, Phase 4 2, Phase 3 1) 2015: 6 trials (Observational 3, Not applicable 1, Phase 4 2) 2016: 10 trials (Observational 5, Not applicable 4, Phase 3 1) 2017: 16 trials (Observational 2, Not applicable 11, Phase 4 2, Phase 3 1) 2018: 28 trials (Observational 11, Not applicable 16, Phase 4 1) 2019: 20 trials (Observational 7, Not applicable 12, Phase 2 1) 2020: 21 trials (Observational 7, Not applicable 12, Phase 4 1, Phase 1 1) 2021: 25 trials (Observational 12, Not applicable 13) 2022: 28 trials (Observational 11, Not applicable 14, Phase 4 2, Phase 1 1) 2023: 34 trials (Observational 15, Not applicable 19) 2024: 30 trials (Observational 12, Not applicable 17, Phase 4 1) 2025: 29 trials (Observational 9, Not applicable 19, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 26
2025 29
2024 30
2023 34
2022 28
2021 25
2020 21
2019 20
2018 28
2017 16

Forecast of the full-year count, planned starts included, not rows of this table: about 31 trials starting in 2026 and about 28 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 24 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 187 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Peri-Implantitis trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 3
Phase 1/2 1
Phase 2 4
Phase 2/3 1
Phase 3 7
Phase 4 17
Not applicable 167
Observational 118

How many Peri-Implantitis trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 25
Recruiting 36
Enrolling by invitation 11
Active, not recruiting 10
Completed 180

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Peri-Implantitis? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Amoxicillin 3

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
2% chlorhexidine 11
Control (placebo) group 3
Metronidazol 3
open flap debridement 3
Non-Surgical Intervention 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Peri-Implantitis trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Death 2 2
Acute myocardial infarction 1 1
Colon cancer 1 1
Diverticulitis 1 1
Facial paralysis 1 1

Which publications cover Peri-Implantitis? (329)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages