Condition (MeSH)
22q11 Deletion Syndrome
ClinicalTrials.gov lists 49 trials for 22q11 Deletion Syndrome or a narrower condition beneath it. Sumitomo Pharma Switzerland GmbH has the most among industry and government lead sponsors, with 7.
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Trials per phase
7 of the 49 trials are tagged with 22q11 Deletion Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did 22q11 Deletion Syndrome trials start? (23)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 3 |
| 2024 | 1 |
| 2023 | 3 |
| 2022 | 1 |
| 2020 | 5 |
| 2018 | 2 |
| 2017 | 2 |
| 2016 | 3 |
| 2015 | 5 |
| 2014 | 1 |
Showing 10 of 23 earlier years.
No forecast is made for this condition: it averages 1.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 53 months across 29 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are 22q11 Deletion Syndrome trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 1/2 | 1 |
| Phase 2 | 8 |
| Phase 2/3 | 1 |
| Phase 3 | 1 |
| Phase 4 | 1 |
| Not applicable | 14 |
| Observational | 19 |
How many 22q11 Deletion Syndrome trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 10 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 1 |
| Completed | 24 |
| Terminated | 8 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most 22q11 Deletion Syndrome trials? (7)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Sumitomo Pharma Switzerland GmbH | 7 |
| National Center for Research Resources (NCRR) | 2 |
| Progenity, Inc. | 2 |
| Aevi Genomic Medicine, LLC, a Cerecor company | 1 |
| Bausch Health Americas, Inc. | 1 |
Showing 5 of 7 sponsors.
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Cultured Thymus Tissue for Implantation (CTTI) | 2 |
| Hematopoietic Stem Cell Transplant | 1 |
| Calcium Chloride/Calcium Gluconate | 1 |
| Rabbit Anti thymocyte globulin | 1 |
| Standard Care | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do 22q11 Deletion Syndrome trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Device related infection | 39 | 4 |
| Pyrexia | 16 | 4 |
| Respiratory failure | 15 | 4 |
| Hypoxia | 10 | 4 |
| Diarrhoea | 7 | 5 |
Showing 5 of 10 adverse events.
Which publications cover 22q11 Deletion Syndrome? (2)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Cognitive remediation for adolescents with 22q11 deletion syndrome (22q11DS): a preliminary study examining effectiveness, feasibility, and fidelity of a hybrid strategy, remote and computer-based intervention. | Schizophrenia research | 2015 | Yes |
| Effects of oropharyngeal surgery on velopharyngeal competence. | Current opinion in otolaryngology & head and neck surgery | 2012 | No |
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.