Condition (MeSH)
Premature Ejaculation
ClinicalTrials.gov lists 104 trials for Premature Ejaculation or a narrower condition beneath it. GlaxoSmithKline has the most among industry and government lead sponsors, with 6.
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Trials per phase
104 of the 104 trials are tagged with Premature Ejaculation itself; the rest are tagged with a narrower condition beneath it.
When did Premature Ejaculation trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 9
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 6 |
| 2025 | 7 |
| 2024 | 9 |
| 2022 | 8 |
| 2021 | 6 |
| 2020 | 4 |
| 2019 | 7 |
| 2018 | 3 |
| 2017 | 6 |
| 2016 | 6 |
Showing 10 of 22 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 7 trials starting in 2026 and about 7 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 20 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 9 months across 55 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Premature Ejaculation trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 9 |
| Phase 1/2 | 2 |
| Phase 2 | 15 |
| Phase 2/3 | 3 |
| Phase 3 | 21 |
| Phase 4 | 4 |
| Not applicable | 33 |
| Observational | 17 |
How many Premature Ejaculation trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 8 |
| Recruiting | 7 |
| Active, not recruiting | 2 |
| Completed | 60 |
| Terminated | 5 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Premature Ejaculation trials? (8)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| GlaxoSmithKline | 6 |
| Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 5 |
| Boston Medical Group | 4 |
| Janssen Research & Development, LLC | 4 |
| Plethora Solutions Ltd | 4 |
Showing 5 of 8 sponsors.
Which drugs are being tested for Premature Ejaculation? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Dapoxetine | 16 |
| GSK958108 | 2 |
| Clomipramine | 2 |
| Epelsiban | 2 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Paroxetine IR | 4 |
| Intervention B | 2 |
| Hyaluronic acid 1% | 2 |
| Intervention A | 2 |
| Exercise | 2 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Premature Ejaculation trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Anaemia | 1 | 1 |
| Burns second degree | 1 | 1 |
| Cholelithiasis | 1 | 1 |
| Concussion | 1 | 1 |
| Contusion | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Premature Ejaculation? (28)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Associations between self-reports of physical activity, interoceptive awareness, autonomic regulation, premature ejaculation, and erectile dysfunction in Chinese men. | International journal of impotence research | 2025 | Yes |
| Comparative evaluation of safety and efficacy of dapoxetine, silodosin, and citalopram in the management of premature ejaculation: a randomized clinical trial. | BMC urology | 2025 | Yes |
| A novel on-demand therapy for lifelong premature ejaculation using a miniature transperineal electrical stimulator-the vPatch: an as-treated analysis. | The journal of sexual medicine | 2023 | Yes |
| The Effect of Pelvic Floor Rehabilitation on Males with Sexual Dysfunction: A Narrative Review. | Sexual medicine reviews | 2022 | Yes |
| The efficacy of regular penis-root masturbation, versus Kegel exercise in the treatment of primary premature ejaculation: A quasi-randomised controlled trial. | Andrologia | 2020 | Yes |
Showing 5 of 28 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.