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Condition (MeSH)

Intraocular Lymphoma

ClinicalTrials.gov lists 165 trials for Intraocular Lymphoma or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 32.

MeSH D064090 Neoplasms Neoplasm C04 C15 C20 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 68 Phase 1/2 Phase 1/2 10 Phase 2 Phase 2 29 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 13 Not applicable Not applicable 21 Observational Observational 22 Unknown Unknown 1 Phase 1 Phase 1 68 Phase 1/2 Phase 1/2 10 Phase 2 Phase 2 29 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 13 Not applicable Not applicable 21 Observational Observational 22 Unknown Unknown 1

Trials per phase (log scale)

165 of the 165 trials are tagged with Intraocular Lymphoma itself; the rest are tagged with a narrower condition beneath it.

Get the Intraocular Lymphoma report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Intraocular Lymphoma trials start? (30)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Not applicable
  • Observational
  • Unknown

Top of scale: 14

1990: 1 trials (Not applicable 1) 1992: 1 trials (Phase 2 1) 1994: 1 trials (Phase 1 1) 1996: 3 trials (Observational 1, Phase 1 2) 1997: 2 trials (Not applicable 1, Phase 1 1) 1998: 5 trials (Phase 2/3 1, Phase 2 2, Phase 1 2) 1999: 14 trials (Not applicable 1, Phase 3 3, Phase 2 1, Phase 1/2 1, Phase 1 8) 2000: 9 trials (Not applicable 1, Phase 3 2, Phase 2 2, Phase 1/2 1, Phase 1 3) 2001: 5 trials (Phase 3 1, Phase 1/2 1, Phase 1 3) 2002: 8 trials (Not applicable 1, Phase 3 1, Phase 2 1, Phase 1 5) 2003: 8 trials (Observational 1, Phase 2 4, Phase 1 3) 2004: 7 trials (Observational 1, Phase 2 1, Phase 1/2 1, Phase 1 4) 2005: 5 trials (Observational 2, Phase 3 1, Phase 2 2) 2006: 4 trials (Not applicable 1, Phase 1 3) 2007: 12 trials (Observational 1, Not applicable 2, Phase 3 2, Phase 2 1, Phase 1 6) 2008: 10 trials (Observational 3, Not applicable 1, Phase 3 2, Phase 1 4) 2009: 10 trials (Unknown 1, Observational 3, Not applicable 1, Phase 3 1, Phase 2 1, Phase 1/2 1, Phase 1 2) 2010: 10 trials (Observational 2, Not applicable 1, Phase 2 3, Phase 1 4) 2011: 8 trials (Observational 1, Not applicable 1, Phase 2 2, Phase 1/2 1, Phase 1 3) 2012: 5 trials (Phase 2 1, Phase 1 4) 2013: 8 trials (Phase 2 2, Phase 1/2 1, Phase 1 5) 2014: 7 trials (Observational 1, Not applicable 1, Phase 2 1, Phase 1/2 1, Phase 1 3) 2015: 5 trials (Not applicable 3, Phase 2 1, Phase 1 1) 2016: 1 trials (Phase 1/2 1) 2018: 1 trials (Phase 2 1) 2021: 2 trials (Observational 1, Not applicable 1) 2023: 1 trials (Observational 1) 2024: 4 trials (Observational 2, Not applicable 1, Phase 2 1) 2025: 1 trials (Observational 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 2
2025 1
2024 4
2023 1
2021 2
2018 1
2016 1
2015 5
2014 7
2013 8

No forecast is made for this condition: it averages 1.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Intraocular Lymphoma trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 68
Phase 1/2 10
Phase 2 29
Phase 2/3 1
Phase 3 13
Not applicable 21
Observational 22
Unknown 1

How many Intraocular Lymphoma trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 2
Recruiting 5
Enrolling by invitation 1
Active, not recruiting 4
Completed 109

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Intraocular Lymphoma trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 32
European Organisation for Research and Treatment of Cancer - EORTC 4
National Institutes of Health Clinical Center (CC) 4

Which drugs are being tested for Intraocular Lymphoma? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
RITUXIMAB 16
Cytoxan 15

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Peripheral blood stem cell transplantation 15
SQ Fludarabine 12
Total Body Irradiation 11
Cyclosporine 0.05% 10
Etoposid 10

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Intraocular Lymphoma trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
1 yr TRM 93 1
Regimen Related Toxicity 63 1
Febrile neutropenia 19 3
Infection/Fever 13 1
Sepsis 11 5

Which publications cover Intraocular Lymphoma? (7)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Prevalence (2)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Primary vitreoretinal large B-cell lymphoma Point prevalence <1 / 1 000 000 Worldwide Not stated Exact
Primary vitreoretinal large B-cell lymphoma Point prevalence <1 / 1 000 000 Worldwide Not stated Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Primary vitreoretinal large B-cell lymphoma 695631 Exact Orphanet Rare Disease Ontology (ORDO)
Primary vitreoretinal large B-cell lymphoma 695631 Exact Orphadata Science knowledge files, Product 1

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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