Organization (Hospital)
Boston Children's Hospital
ClinicalTrials.gov lists Boston Children's Hospital as lead sponsor of 605 trials. It has 166 active development programs and 105 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 41 registered with a 2026 start date. The hollow diamonds on the dashed line are a forecast of the full-year count, planned starts included: about 46 in 2026 and about 43 in 2027, the average of the 24 months through September, counted as registered and carried forward. The columns, the lighter one included, count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. This method has not been backtested on organizations. In backtests on conditions with as many trial starts a year as this organization (20 to 100), forecasts made part-way through the year were typically off by about 18 percent and ran about 14 percent low against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. 8 trials are registered to start in 2027 or later.
This page covers Boston Children's Hospital: 605 lead-sponsored trials and 2 legal-entity registrations.
Disease areas (473)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Heart Defects, Congenital | 55 |
| Pain | 35 |
| Autism Spectrum Disorder | 32 |
| Obesity | 32 |
| Substance-Related Disorders | 28 |
Showing 5 of 473 disease areas.
Trials by start year as sponsor or collaborator (32)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 8 trials are registered to start in 2027 or later, and not listed here.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 41 |
| 2025 | 42 |
| 2024 | 40 |
| 2023 | 36 |
| 2022 | 31 |
| 2021 | 47 |
| 2020 | 60 |
| 2019 | 54 |
| 2018 | 53 |
| 2017 | 43 |
Showing 10 of 32 years.
Prediction, not a registry value: median of 36 months from start to primary completion across 58 trials still running at the 2026-10-09 snapshot; registered median of 32 months across 352 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (166)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| FLUDARABINE | Anemia, Aplastic | Phase 3 | 2 |
| FLUDARABINE | Anemia | Phase 3 | 2 |
| Calcium-vitamin D3 | Colitis, Ulcerative | Phase 3 | 2 |
| Calcium-vitamin D3 | Crohn Disease | Phase 3 | 2 |
| Calcium-vitamin D3 | Inflammatory Bowel Diseases | Phase 3 | 2 |
Showing 5 of 166 active programs.
Approved assets (105)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| DEXMEDETOMIDINE | 6 |
| Calcium-vitamin D3 | 3 |
| High bile acid binding blenderized diet | 3 |
| Low bile acid binding blenderized diet | 3 |
| Ropivacaine | 3 |
Showing 5 of 105 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 34% hit target (n=203) | 24% on time (n=187) |
Journals published in (926)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| The Journal of pediatrics | 77 |
| Pediatrics | 73 |
| Circulation | 48 |
| The New England journal of medicine | 48 |
| Journal of pediatric gastroenterology and nutrition | 32 |
Showing 5 of 926 journals.
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 11 | 2 | 2022-11-01 |
Financing and grant events (2,411)
Shown in this order: most recent first.
| Date | Round type | Amount (USD) | Source |
|---|---|---|---|
| 2025-09-30 | NIH grant | 1,000,000 | Reporter |
| 2025-09-30 | NIH grant | 1,112,104 | Reporter |
| 2025-09-26 | NIH grant | 421,592 | Reporter |
| 2025-09-25 | NIH grant | 1,673,641 | Reporter |
| 2025-09-24 | NIH grant | 802,141 | Reporter |
Showing 5 of 2,411 events.
Organization relationships (373)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| Government of the United States of America | Co sponsors trial with | 74 |
| Children's Hospital of Philadelphia | Co sponsors trial with | 35 |
| Cincinnati Children's Hospital Medical Center | Co sponsors trial with | 31 |
| University of California System | Co sponsors trial with | 31 |
| Harris Health System | Co sponsors trial with | 25 |
Showing 5 of 373 relationships.
Latest dated events (3,281)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2031-01-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2027-07-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2027-04 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2027-04-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2027-02-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 3,281 events.
CLIA clinical laboratory certificates (2)
Shown in this order: active first, then certificate type.
| Lab | Certificate | Status |
|---|---|---|
| BOSTON CHILDREN'S HOSPITAL | Certificate of accreditation | Active |
| CHILDREN'S HOSPITAL BOSTON | Certificate for PPM procedures | Active |
Biomarker capability evidence (1,054)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| AARS2 | Trial sponsor | Named in trial inclusion criteria |
| AARS2 | Trial sponsor | Named in trial inclusion criteria |
| ABL1 | Trial sponsor | Named in trial inclusion criteria |
| ABL1 | Trial collaborator | Named in trial inclusion criteria |
| ABO | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 1,054 evidence rows.
Biomarkers this organization publishes on (2,798)
Shown in this order: most publications first.
Showing 5 of 2,798 biomarkers.
On Scientist.com
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