Organization (Industry)
Impulse Dynamics (United States)
ClinicalTrials.gov lists Impulse Dynamics (United States) as lead sponsor of 13 trials.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 0 registered with a 2026 start date. The dashed outline is the pace from the 0 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 1.6 trial starts a year over the five years to September, under the 5 a year the method needs.
This page covers Impulse Dynamics (United States): 13 lead-sponsored trials and 1 legal-entity registration.
Disease areas (16)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Heart Failure | 16 |
| Heart Failure, Diastolic | 2 |
| Atrial Fibrillation | 1 |
| Bundle-Branch Block | 1 |
| Cardiomyopathies | 1 |
Showing 5 of 16 disease areas.
Trials by start year as sponsor or collaborator (10)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2025 | 4 |
| 2023 | 2 |
| 2022 | 2 |
| 2021 | 1 |
| 2020 | 1 |
| 2018 | 1 |
| 2017 | 2 |
| 2014 | 1 |
| 2011 | 2 |
| 2005 | 1 |
Recruitment duration, a model prediction: none of the 13 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 1 of 3 hit target (n=3) | 0 of 4 on time (n=4) |
Journals published in (38)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| European journal of heart failure | 6 |
| Arquivos brasileiros de cardiologia | 4 |
| Circulation | 4 |
| International journal of cardiology | 4 |
| ESC heart failure | 3 |
Showing 5 of 38 journals.
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 93 | 10 | 2025-07-29 |
Financing and grant events (5)
Shown in this order: most recent first.
| Date | Round type | Amount (USD) | Source |
|---|---|---|---|
| 2025-02-20 | Private placement | 84,130,000 | Form d |
| 2024-02-05 | Private placement | 136,499,993 | Form d |
| 2022-02-11 | Private placement | 91,385,181 | Form d |
| 2020-12-18 | Private placement | 60,000,000 | Form d |
| 2019-11-20 | Private placement | 45,250,000 | Form d |
FDA inspection record (1)
| Latest classification | Inspections |
|---|---|
| NAI | 3 |
FDA recalls (1)
| Product | Classification | Initiated |
|---|---|---|
| OPTIMIZER model CCM X11 implantable pulse generator (IPG) devices - Smart Mini and Lite | Class II | 2024-01-05 |
FDA import refusals (1)
| Refused import lines | Latest refusal |
|---|---|
| 1 | 2021-12-16 |
Organization relationships (2)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| I2medi Comercial Medica LTDA | Co sponsors trial with | 1 |
| InCor Heart Institute | Co sponsors trial with | 1 |
Latest dated events (120)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2025-11-18 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-11-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-07-29 | Patent granted | Granted US patents (PatentsView / USPTO) |
| 2025-07-10 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-07-01 | Patent granted | Granted US patents (PatentsView / USPTO) |
Showing 5 of 120 events.
Biomarker capability evidence (17)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| AGT | Trial sponsor | Named in trial inclusion criteria |
| AGT | Trial sponsor | Named in trial inclusion criteria |
| AGT | Trial sponsor | Named in trial inclusion criteria |
| MME | Trial sponsor | Named in trial inclusion criteria |
| NPPB | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 17 evidence rows.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, active development programs, approved assets, sec-reported annual financials, fda warning letters, fda untitled letters, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, clia clinical laboratory certificates, and biomarkers this organization publishes on.