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Organization (Other)

HIV Prevention Trials Network

ClinicalTrials.gov lists HIV Prevention Trials Network as lead sponsor of 24 trials. It has 23 active development programs and 1 approved asset.

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4 0 2002 2026

Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.

2026 is partial: 3 registered with a 2026 start date. The dashed outline is the pace from the 3 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 1.8 trial starts a year over the five years to September, under the 5 a year the method needs.

This page covers HIV Prevention Trials Network: 24 lead-sponsored trials and 0 legal-entity registrations.

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Disease areas (7)

Shown in this order: most trials first.

Disease areas
Disease area Trials
HIV Infections 21
Acquired Immunodeficiency Syndrome 2
COVID-19 1
HIV Seropositivity 1
Hepatitis B 1

Trials by start year as sponsor or collaborator (19)

Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Show the table of trials by start year as sponsor or collaborator
Trials by start year as sponsor or collaborator
Year Trials started
2026 (partial year) 3
2025 1
2024 2
2023 2
2022 1
2021 3
2020 2
2017 1
2016 2
2015 2

Recruitment duration, a model prediction: none of the 24 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

Active development programs (23)

Shown in this order: max phase, then active trials.

Active development programs
Drug Disease area Max phase Trials
HIV PrEP - choice of F/TDF, F/TAF, or CAB-LA HIV Infections Phase 3 1
STI PEP - Doxycycline as Doxy-PEP Acquired Immunodeficiency Syndrome Phase 3 1
HIV PrEP - choice of F/TDF, F/TAF, or CAB-LA Acquired Immunodeficiency Syndrome Phase 3 1
HIV PrEP - choice of F/TDF, F/TAF, or CAB-LA Hepatitis B Phase 3 1
STI PEP - Doxycycline as Doxy-PEP Hepatitis B Phase 3 1

Approved assets (1)

Approved assets
Drug Trials
TRUVADA 1

Sponsor delivery record (1)

Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.

Sponsor delivery record
Enrollment Timeline
14% hit target (n=7) 11% on time (n=9)

Journals published in (69)

Shown in this order: most published in first.

Journals published in
Journal Publications
Journal of acquired immune deficiency syndromes (1999) 11
Journal of the International AIDS Society 11
PLoS medicine 9
PloS one 9
The New England journal of medicine 8

Organization relationships (1)

Organization relationships
Related organization Relationship Evidence
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections Co sponsors trial with 3

Latest dated events (34)

Shown in this order: newest first.

Latest dated events
Date Event Source
2026-09-01 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-08-27 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-05-15 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2025-12-10 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2024-04-02 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))

Biomarker capability evidence (21)

Shown in this order: tier desc, then gene symbol.

Biomarker capability evidence
Gene Role Evidence
CD4 Trial collaborator Named in trial inclusion criteria
CD4 Trial collaborator Named in trial inclusion criteria
CD4 Trial collaborator Named in trial inclusion criteria
ACTG1 Trial sponsor Named in trial exclusion criteria
APOH Trial collaborator Named in trial exclusion criteria

Not on this page

Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, us granted patents, sec-reported annual financials, financing and grant events, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, clia clinical laboratory certificates, and biomarkers this organization publishes on.