Organization (Nonprofit)
Jaeb Center for Health Research
ClinicalTrials.gov lists Jaeb Center for Health Research as lead sponsor of 129 trials. It has 23 active development programs and 13 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 10 registered with a 2026 start date. The hollow diamonds on the dashed line are a forecast of the full-year count, planned starts included: about 12 in 2026 and about 11 in 2027, the average of the 24 months through September, counted as registered and carried forward. The columns, the lighter one included, count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. This method has not been backtested on organizations. In backtests on conditions with as many trial starts a year as this organization (5 to 20), forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. 1 trial is registered to start in 2027 or later.
This page covers Jaeb Center for Health Research: 129 lead-sponsored trials and 1 legal-entity registration.
Disease areas (38)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Diabetes Mellitus | 91 |
| Diabetes Mellitus, Type 1 | 63 |
| Vision Disorders | 26 |
| Amblyopia | 24 |
| Diabetes Mellitus, Type 2 | 13 |
Showing 5 of 38 disease areas.
Trials by start year as sponsor or collaborator (27)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 10 |
| 2025 | 10 |
| 2024 | 6 |
| 2023 | 12 |
| 2022 | 7 |
| 2021 | 9 |
| 2020 | 9 |
| 2019 | 8 |
| 2018 | 9 |
| 2017 | 11 |
Showing 10 of 27 years.
Prediction, not a registry value: median of 36 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 26 months across 91 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (23)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| BEVACIZUMAB | Retinopathy of Prematurity | Phase 3 | 3 |
| Atropine | Myopia | Phase 3 | 2 |
| BOTULINUM TOXIN TYPE-A | Esotropia | Phase 3 | 1 |
| Fluocinolone Acetonide | Vision Disorders | Phase 3 | 1 |
| BOTULINUM TOXIN TYPE-A | Strabismus | Phase 3 | 1 |
Showing 5 of 23 active programs.
Approved assets (13)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Atropine | 9 |
| Anti-Vascular Endothelial Growth Factor | 1 |
| BEVACIZUMAB | 4 |
| METFORMIN | 2 |
| Faricimab | 2 |
Showing 5 of 13 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 47% hit target (n=36) | 22% on time (n=32) |
Journals published in (116)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| Diabetes care | 90 |
| Diabetes technology & therapeutics | 61 |
| JAMA ophthalmology | 42 |
| Ophthalmology | 40 |
| The New England journal of medicine | 27 |
Showing 5 of 116 journals.
Financing and grant events (26)
Shown in this order: most recent first.
| Date | Round type | Amount (USD) | Source |
|---|---|---|---|
| 2025-09-02 | NIH grant | 2,345,176 | Reporter |
| 2025-07-14 | NIH grant | 443,042 | Reporter |
| 2025-02-14 | NIH grant | 8,000,000 | Reporter |
| 2025-02-14 | NIH grant | 10,500,000 | Reporter |
| 2024-08-05 | NIH grant | 400,000 | Reporter |
Showing 5 of 26 events.
FDA inspection record (1)
| Latest classification | Inspections |
|---|---|
| NAI | 1 |
Organization relationships (34)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| Cambridge University Hospitals NHS Foundation Trust | Co sponsors trial with | 5 |
| Pediatric Eye Disease Investigator Group | Co sponsors trial with | 3 |
| Marc Breton | Co sponsors trial with | 2 |
| Roche (Switzerland) | Co sponsors trial with | 2 |
| Medical University of Vienna | Co sponsors trial with | 2 |
Showing 5 of 34 relationships.
Latest dated events (204)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2027-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-10-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-07-31 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-06-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-06-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 204 events.
Biomarker capability evidence (276)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ACSBG1 | Trial sponsor | Named in trial inclusion criteria |
| AICDA | Trial collaborator | Named in trial inclusion criteria |
| AICDA | Trial collaborator | Named in trial inclusion criteria |
| AICDA | Trial collaborator | Named in trial inclusion criteria |
| AICDA | Trial collaborator | Named in trial inclusion criteria |
Showing 5 of 276 evidence rows.
Biomarkers this organization publishes on (29)
Shown in this order: most publications first.
Showing 5 of 29 biomarkers.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, us granted patents, sec-reported annual financials, fda warning letters, fda untitled letters, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, and clia clinical laboratory certificates.