Organization (Hospital)
Moorfields Eye Hospital NHS Foundation Trust
ClinicalTrials.gov lists Moorfields Eye Hospital NHS Foundation Trust as lead sponsor of 48 trials, counting the companies grouped under it. Moorfields Eye Hospital NHS Foundation Trust itself has 5 active development programs and 7 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. Companies grouped under this one are not included. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 2 registered with a 2026 start date. The dashed outline is the pace from the 2 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 3.6 trial starts a year over the five years to September, under the 5 a year the method needs.
This page covers Moorfields Eye Hospital NHS Foundation Trust and 1 company grouped under it: 48 lead-sponsored trials (48 its own, 0 in the grouped companies) and 3 legal-entity registrations (1 its own, 2 in the grouped companies).
Companies grouped under this page (1)
| Company | Lead trials | Legal entities |
|---|---|---|
| MOORFIELDS EYE CHARITY | 0 | 2 |
Disease areas (52)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Macular Degeneration | 9 |
| Glaucoma | 8 |
| Keratoconus | 5 |
| Diabetes Mellitus | 4 |
| Diabetic Retinopathy | 4 |
Showing 5 of 52 disease areas.
Trials by start year as sponsor or collaborator (22)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 2 |
| 2024 | 5 |
| 2023 | 1 |
| 2022 | 6 |
| 2021 | 5 |
| 2020 | 1 |
| 2019 | 9 |
| 2018 | 5 |
| 2017 | 4 |
Showing 10 of 22 years.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (5)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| FLUOROURACIL | Glaucoma | Phase 3 | 2 |
| FLUOROURACIL | Glaucoma, Open-Angle | Phase 3 | 1 |
| AFLIBERCEPT | Macular Edema | Phase 2 | 1 |
| AFLIBERCEPT | Retinitis Pigmentosa | Phase 2 | 1 |
| PF-05206388 | Macular Degeneration | Phase 1 | 1 |
Approved assets (7)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Ranibizumab | 3 |
| AFLIBERCEPT | 2 |
| Primary Medical Treatment Pathway | 1 |
| DEXAMETHASONE | 2 |
| FLUOROURACIL | 2 |
Showing 5 of 7 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 60% hit target (n=25) | 29% on time (n=24) |
Journals published in (53)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| Ophthalmology | 16 |
| The British journal of ophthalmology | 12 |
| Eye (London, England) | 5 |
| Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie | 5 |
| BMJ open | 4 |
Showing 5 of 53 journals.
Manufacturing and distribution sites (1)
| Facility | Location | Regulators | Member organization |
|---|---|---|---|
| MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST | LONDON, GB | EMA |
Organization relationships (42)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| University of California System | Co sponsors trial with | 4 |
| University of Oxford | Co sponsors trial with | 3 |
| Great Ormond Street Hospital for Children NHS Foundation Trust | Co sponsors trial with | 2 |
| The Special Trustees Of Moorfields Eye Hospital General Fund Patient Welfare And Amenities | Linked charity of | 1 |
| The Special Trustees Of Moorfields Eye Hospital General Fund Diagnostic Support | Linked charity of | 1 |
Showing 5 of 42 relationships.
Latest dated events (75)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2026-09-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-09 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-06-12 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-01-26 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2024-10-09 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 75 events.
Biomarker capability evidence (44)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| AMD1 | Trial collaborator | Named in trial inclusion criteria |
| CHM | Trial collaborator | Named in trial inclusion criteria |
| CNGB1 | Trial collaborator | Named in trial inclusion criteria |
| KCNMA1 | Trial collaborator | Named in trial inclusion criteria |
| PVR | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 44 evidence rows.
Biomarkers this organization publishes on (20)
Shown in this order: most publications first.
Showing 5 of 20 biomarkers.
Not on this page
Checked, with nothing recorded for this organization: related companies not grouped here, us granted patents, sec-reported annual financials, financing and grant events, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, climate targets, as filed, workforce and board diversity, as filed, and clia clinical laboratory certificates.