Organization (Other)
Italian Sarcoma Group
ClinicalTrials.gov lists Italian Sarcoma Group as lead sponsor of 31 trials. It has 22 active development programs and 13 approved assets.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 0 registered with a 2026 start date. The dashed outline is the pace from the 0 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs. 1 trial is registered to start in 2027 or later.
This page covers Italian Sarcoma Group: 31 lead-sponsored trials and 1 legal-entity registration.
Disease areas (22)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Sarcoma | 25 |
| Osteosarcoma | 11 |
| Leiomyosarcoma | 3 |
| Liposarcoma | 3 |
| Sarcoma, Ewing | 3 |
Showing 5 of 22 disease areas.
Trials by start year as sponsor or collaborator (16)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2024 | 2 |
| 2021 | 5 |
| 2020 | 3 |
| 2019 | 2 |
| 2018 | 1 |
| 2017 | 3 |
| 2016 | 3 |
| 2014 | 4 |
| 2011 | 3 |
Showing 10 of 16 years.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (22)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| Trabectedin | Sarcoma | Phase 2 | 5 |
| GEMCITABINE | Sarcoma | Phase 2 | 1 |
| No Intervention: Observational Cohort | Sarcoma | Phase 2 | 1 |
| Lurbinectedin | Sarcoma | Phase 2 | 1 |
| Lurbinectedin | Desmoplastic Small Round Cell Tumor | Phase 2 | 1 |
Showing 5 of 22 active programs.
Approved assets (13)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Trabectedin | 7 |
| Sorafenib | 2 |
| Irinotecan | 1 |
| Liposomal Doxorubicin | 1 |
| Dacarbazine | 1 |
Showing 5 of 13 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 63% hit target (n=16) | 36% on time (n=14) |
Journals published in (121)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 27 |
| The Lancet. Oncology | 19 |
| European journal of cancer (Oxford, England : 1990) | 17 |
| Cancer | 13 |
| Annals of oncology : official journal of the European Society for Medical Oncology | 12 |
Showing 5 of 121 journals.
Organization relationships (11)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| European Organisation for Research and Treatment of Cancer - EORTC | Co sponsors trial with | 2 |
| Spanish Research Group on Sarcomas | Co sponsors trial with | 2 |
| PharmaMar (Spain) | Co sponsors trial with | 2 |
| Associazione Italiana Ematologia Oncologia Pediatrica | Co sponsors trial with | 1 |
| Eisai (Japan) | Co sponsors trial with | 1 |
Showing 5 of 11 relationships.
Latest dated events (35)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2027-01-30 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-11-21 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2024-03-29 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2024-01-29 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2021-10-29 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 35 events.
Biomarker capability evidence (92)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ALB | Trial sponsor | Named in trial inclusion criteria |
| ALB | Trial sponsor | Named in trial inclusion criteria |
| ALB | Trial sponsor | Named in trial inclusion criteria |
| ALB | Trial sponsor | Named in trial inclusion criteria |
| BCOR | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 92 evidence rows.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, us granted patents, sec-reported annual financials, financing and grant events, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, clia clinical laboratory certificates, and biomarkers this organization publishes on.