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Clinical trial

Phase II Study of the PARP Inhibitor Talazoparib in Advanced Cancer Patients With Somatic Alterations in BRCA1/2, Mutations/Deletions in Other BRCA Pathway Genes and Germline Mutation in BRCA1/2 (Not Breast or Ovarian Cancer)

NCT02286687 is registered in ClinicalTrials.gov with M.D. Anderson Cancer Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase II Study of the PARP Inhibitor Talazoparib in Advanced Cancer Patients With Somatic Alterations in BRCA1/2, Mutations/Deletions in Other BRCA Pathway Genes and Germline Mutation in BRCA1/2 (Not Breast or Ovarian Cancer)
Lead sponsor
M.D. Anderson Cancer Center
Phase
Phase 2
Overall status
Active, not recruiting
Start date
December 22, 2014
Completion date
December 31, 2026
Enrollment
150 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

advanced malignant neoplasm, atm gene mutation, brca1 gene mutation, brca2 gene mutation, metastatic malignant neoplasm, palb2 gene mutation, recurrent malignant neoplasm, refractory malignant neoplasm