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Clinical trial

A Phase I Clinical Trial of Trametinib in Combination With TAS-102 in Patients With Chemotherapy-Resistant RAS-Mutated (PIK3CA/PTEN-Wild-Type) Metastatic Colorectal Cancer

NCT03317119 is registered in ClinicalTrials.gov with City of Hope Medical Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I Clinical Trial of Trametinib in Combination With TAS-102 in Patients With Chemotherapy-Resistant RAS-Mutated (PIK3CA/PTEN-Wild-Type) Metastatic Colorectal Cancer
Lead sponsor
City of Hope Medical Center
Phase
Phase 1
Overall status
Completed
Start date
April 11, 2018
Completion date
July 14, 2023
Enrollment
26 (actual)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

metastatic colon carcinoma, metastatic colorectal carcinoma, metastatic rectal carcinoma, ras family gene mutation, stage iii colon cancer ajcc v7, stage iii colorectal cancer ajcc v7, stage iii rectal cancer ajcc v7, stage iiia colon cancer ajcc v7, stage iiia colorectal cancer ajcc v7, stage iiia rectal cancer ajcc v7, stage iiib colon cancer ajcc v7, stage iiib colorectal cancer ajcc v7, stage iiib rectal cancer ajcc v7, stage iiic colon cancer ajcc v7, stage iiic colorectal cancer ajcc v7, stage iiic rectal cancer ajcc v7, stage iv colon cancer ajcc v7, stage iv colorectal cancer ajcc v7, stage iv rectal cancer ajcc v7, stage iva colon cancer ajcc v7, stage iva colorectal cancer ajcc v7, stage iva rectal cancer ajcc v7, stage ivb colon cancer ajcc v7, stage ivb colorectal cancer ajcc v7, stage ivb rectal cancer ajcc v7