Clinical trial
A First-in-human Phase 1 Dose-escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation
NCT07458347 is registered in ClinicalTrials.gov with Kestrel Therapeutics, Inc. as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- A First-in-human Phase 1 Dose-escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation
- Lead sponsor
- Kestrel Therapeutics, Inc.
- Phase
- Phase 1
- Overall status
- Recruiting
- Start date
- April 21, 2026
- Completion date
- May 31, 2028
- Enrollment
- 145 (estimated)
- Sites
- 9
Conditions
As the registry lists them; a condition with its own page is linked.
kras-mutant colorectal cancer (crc), kras-mutant non-small cell lung cancer (nsclc), kras-mutant pancreatic ductal adenocarcinoma (pdac), other kras-mutant solid tumors