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Clinical trial

Phase I Study of Adoptive Immunotherapy With CD8+ and CD4+ Memory T Cells Transduced to Express an HA-1-Specific T Cell Receptor (TCR) for Children and Adults With Recurrent Acute Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation (HCT)

NCT03326921 is registered in ClinicalTrials.gov with Fred Hutchinson Cancer Center as lead sponsor.

NCT NCT03326921
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Registry record

As filed in ClinicalTrials.gov.

Title
Phase I Study of Adoptive Immunotherapy With CD8+ and CD4+ Memory T Cells Transduced to Express an HA-1-Specific T Cell Receptor (TCR) for Children and Adults With Recurrent Acute Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation (HCT)
Lead sponsor
Fred Hutchinson Cancer Center
Phase
Phase 1
Overall status
Recruiting
Start date
February 23, 2018
Completion date
July 16, 2028
Enrollment
24 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

acute biphenotypic leukemia, acute lymphoblastic leukemia, acute myeloid leukemia, acute undifferentiated leukemia, blast phase chronic myeloid leukemia, bcr-abl1 positive, chronic myeloid leukemia, chronic myeloid leukemia, bcr-abl1 positive, chronic myelomonocytic leukemia, juvenile myelomonocytic leukemia, leukemia, minimal residual disease, mixed phenotype acute leukemia, myelodysplastic syndrome, recurrent acute biphenotypic leukemia, recurrent acute lymphoblastic leukemia, recurrent acute myeloid leukemia, recurrent acute undifferentiated leukemia, recurrent blastic plasmacytoid dendritic cell neoplasm, recurrent childhood acute lymphoblastic leukemia, recurrent childhood acute myeloid leukemia, recurrent chronic myeloid leukemia, bcr-abl1 positive, recurrent chronic myelomonocytic leukemia, recurrent mixed phenotype acute leukemia, recurrent myelodysplastic syndrome, refractory acute lymphoblastic leukemia, refractory adult acute lymphoblastic leukemia, refractory blastic plasmacytoid dendritic cell neoplasm, refractory chronic myeloid leukemia, bcr-abl1 positive, refractory myelodysplastic syndrome