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Clinical trial

A Phase 1 Study of AGEN1181, an Fc-Engineered Anti-CTLA-4 Monoclonal Antibody as Monotherapy and in Combination With AGEN2034 (Balstilimab), an Anti-PD-1 Monoclonal Antibody, in Subjects With Advanced Cancer

NCT03860272 is registered in ClinicalTrials.gov with Agenus Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1 Study of AGEN1181, an Fc-Engineered Anti-CTLA-4 Monoclonal Antibody as Monotherapy and in Combination With AGEN2034 (Balstilimab), an Anti-PD-1 Monoclonal Antibody, in Subjects With Advanced Cancer
Lead sponsor
Agenus Inc.
Phase
Phase 1
Overall status
Active, not recruiting
Start date
March 20, 2019
Completion date
December 31, 2027
Enrollment
499 (actual)
Sites
18

Conditions

As the registry lists them; a condition with its own page is linked.

advanced cancer, angiosarcoma, colorectal cancer without liver metastases, endometrial cancer, fibrolamellar carcinoma, non-small-cell lung cancer, ovarian cancer, prostate cancer