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Condition (MeSH)

Prostatic Neoplasms

ClinicalTrials.gov lists 6,479 trials for Prostatic Neoplasms or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 196.

MeSH D011471 Neoplasms Neoplasm C04 C12
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Phase 1 Phase 1 791 Phase 1/2 Phase 1/2 397 Phase 2 Phase 2 1,461 Phase 2/3 Phase 2/3 78 Phase 3 Phase 3 522 Phase 4 Phase 4 123 Not applicable Not applicable 1,800 Observational Observational 1,277 Phase 1 Phase 1 791 Phase 1/2 Phase 1/2 397 Phase 2 Phase 2 1,461 Phase 2/3 Phase 2/3 78 Phase 3 Phase 3 522 Phase 4 Phase 4 123 Not applicable Not applicable 1,800 Observational Observational 1,277

Trials per phase (log scale)

2 more sections with rows

6,427 of the 6,479 trials are tagged with Prostatic Neoplasms itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Prostatic Neoplasms trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 11 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 374

1990: 4 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 1) 1991: 2 trials (Observational 1, Phase 1 1) 1992: 3 trials (Phase 3 3) 1993: 6 trials (Observational 5, Not applicable 1) 1994: 6 trials (Observational 1, Phase 3 3, Phase 1/2 1, Phase 1 1) 1995: 17 trials (Observational 3, Phase 3 9, Phase 2 1, Phase 1/2 1, Phase 1 3) 1996: 14 trials (Observational 2, Not applicable 1, Phase 3 6, Phase 2 4, Phase 1 1) 1997: 26 trials (Observational 1, Not applicable 5, Phase 3 6, Phase 2 7, Phase 1/2 2, Phase 1 5) 1998: 39 trials (Observational 5, Not applicable 1, Phase 3 9, Phase 2 13, Phase 1/2 3, Phase 1 8) 1999: 48 trials (Observational 3, Not applicable 2, Phase 3 11, Phase 2/3 1, Phase 2 16, Phase 1/2 5, Phase 1 10) 2000: 60 trials (Observational 3, Not applicable 1, Phase 3 10, Phase 2 28, Phase 1/2 4, Phase 1 14) 2001: 78 trials (Observational 5, Not applicable 6, Phase 4 1, Phase 3 12, Phase 2/3 2, Phase 2 35, Phase 1/2 6, Phase 1 11) 2002: 96 trials (Observational 11, Not applicable 9, Phase 4 6, Phase 3 11, Phase 2/3 3, Phase 2 41, Phase 1/2 7, Phase 1 8) 2003: 119 trials (Observational 12, Not applicable 17, Phase 4 8, Phase 3 19, Phase 2/3 1, Phase 2 44, Phase 1/2 6, Phase 1 12) 2004: 136 trials (Observational 22, Not applicable 12, Phase 4 5, Phase 3 15, Phase 2/3 2, Phase 2 52, Phase 1/2 12, Phase 1 16) 2005: 164 trials (Observational 20, Not applicable 28, Phase 4 4, Phase 3 23, Phase 2/3 3, Phase 2 50, Phase 1/2 15, Phase 1 21) 2006: 185 trials (Observational 22, Not applicable 27, Phase 4 6, Phase 3 21, Phase 2/3 7, Phase 2 56, Phase 1/2 17, Phase 1 29) 2007: 189 trials (Observational 29, Not applicable 34, Phase 4 4, Phase 3 22, Phase 2/3 1, Phase 2 66, Phase 1/2 7, Phase 1 26) 2008: 178 trials (Observational 32, Not applicable 36, Phase 4 2, Phase 3 16, Phase 2 55, Phase 1/2 12, Phase 1 25) 2009: 197 trials (Observational 33, Not applicable 45, Phase 4 3, Phase 3 27, Phase 2/3 2, Phase 2 47, Phase 1/2 13, Phase 1 27) 2010: 166 trials (Observational 33, Not applicable 36, Phase 4 2, Phase 3 12, Phase 2/3 2, Phase 2 41, Phase 1/2 17, Phase 1 23) 2011: 208 trials (Observational 40, Not applicable 54, Phase 4 7, Phase 3 16, Phase 2/3 2, Phase 2 55, Phase 1/2 8, Phase 1 26) 2012: 215 trials (Observational 32, Not applicable 62, Phase 4 5, Phase 3 17, Phase 2/3 4, Phase 2 58, Phase 1/2 12, Phase 1 25) 2013: 223 trials (Observational 47, Not applicable 64, Phase 4 3, Phase 3 13, Phase 2/3 2, Phase 2 58, Phase 1/2 14, Phase 1 22) 2014: 270 trials (Observational 53, Not applicable 87, Phase 4 4, Phase 3 18, Phase 2/3 1, Phase 2 62, Phase 1/2 9, Phase 1 36) 2015: 253 trials (Observational 68, Not applicable 82, Phase 4 6, Phase 3 13, Phase 2/3 1, Phase 2 42, Phase 1/2 13, Phase 1 28) 2016: 277 trials (Observational 60, Not applicable 86, Phase 4 6, Phase 3 16, Phase 2/3 5, Phase 2 50, Phase 1/2 13, Phase 1 41) 2017: 278 trials (Observational 65, Not applicable 94, Phase 4 6, Phase 3 12, Phase 2/3 1, Phase 2 59, Phase 1/2 12, Phase 1 29) 2018: 288 trials (Observational 53, Not applicable 104, Phase 4 2, Phase 3 13, Phase 2/3 7, Phase 2 62, Phase 1/2 19, Phase 1 28) 2019: 304 trials (Observational 68, Not applicable 92, Phase 4 7, Phase 3 14, Phase 2/3 6, Phase 2 62, Phase 1/2 16, Phase 1 39) 2020: 307 trials (Observational 79, Not applicable 93, Phase 4 1, Phase 3 25, Phase 2/3 6, Phase 2 46, Phase 1/2 18, Phase 1 39) 2021: 331 trials (Observational 71, Not applicable 109, Phase 4 3, Phase 3 21, Phase 2/3 6, Phase 2 63, Phase 1/2 16, Phase 1 42) 2022: 279 trials (Observational 63, Not applicable 119, Phase 4 3, Phase 3 15, Phase 2 39, Phase 1/2 15, Phase 1 25) 2023: 339 trials (Other 1, Observational 78, Not applicable 123, Phase 4 5, Phase 3 25, Phase 2/3 4, Phase 2 48, Phase 1/2 18, Phase 1 37) 2024: 374 trials (Observational 91, Not applicable 116, Phase 4 12, Phase 3 16, Phase 2/3 2, Phase 2 67, Phase 1/2 24, Phase 1 46) 2025: 344 trials (Observational 75, Not applicable 124, Phase 4 4, Phase 3 23, Phase 2/3 1, Phase 2 53, Phase 1/2 27, Phase 1 37)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 378
2025 344
2024 374
2023 339
2022 279
2021 331
2020 307
2019 304
2018 288
2017 278

Forecast of the full-year count, planned starts included, not rows of this table: about 420 trials starting in 2026 and about 380 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 818 trials still running at the 2026-10-09 snapshot; registered median of 35 months across 3,837 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Prostatic Neoplasms trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 791
Phase 1/2 397
Phase 2 1,461
Phase 2/3 78
Phase 3 522
Phase 4 123
Not applicable 1,800
Observational 1,277
Expanded access 29
Unknown 1

How many Prostatic Neoplasms trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 238
Recruiting 999
Enrolling by invitation 40
Active, not recruiting 522
Available 6

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Prostatic Neoplasms trials? (5)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 196
AstraZeneca 70
Novartis Pharmaceuticals 56
Bayer 49
Janssen Research & Development, LLC 48

Which drugs are being tested for Prostatic Neoplasms? (6)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Abiraterone 212
Prednisone 212
Enzalutamide 193
Bicalutamide 112
Apalutamide 93

Interventions as named in the registry (9)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Docetetaxel 267
Lupron / Leuprolide acetate 120
Radiation Therapy 104
Goserelin Depot 94
Degarelix 80 mg / Degarelix 80 mg 91

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Prostatic Neoplasms trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 1,432 192
Anaemia 1,143 151
Fatigue 940 166
Urinary tract infection 850 157
Dehydration 838 215

Which publications cover Prostatic Neoplasms? (5,472)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Discovery of BMS-986365, a First-in-Class Dual Androgen Receptor Ligand-Directed Degrader and Antagonist, for the Treatment of Advanced Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2026 Yes
PROSTest, a Multigene Liquid Biopsy Signature, Effectively Stratifies Patients With High PSA for Prostate Biopsy. The Prostate 2026 Yes
Assessing Quality and Adherence to PI-RADSv2.1 Minimum Technical Standards of Prostate MRI in NRG-GU005. Journal of magnetic resonance imaging : JMRI 2026 Yes
Ultra-hypofractionated radiotherapy combined with HDR brachytherapy: An optimized treatment. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2026 Yes
Capivasertib plus abiraterone in PTEN-deficient metastatic hormone-sensitive prostate cancer: CAPItello-281 phase III study. Annals of oncology : official journal of the European Society for Medical Oncology 2026 Yes

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages