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Clinical trial

A Phase 1 Open-Label, First-in-human, Dose Escalation and Expansion Study to Determine the Safety, Tolerability, Dosimetry, Pharmacokinetics, and Preliminary Efficacy of 212Pb-DOTAM-GRPR1 in Adult Participants With Recurrent or Metastatic GRPR-expressing Tumors

NCT05283330 is registered in ClinicalTrials.gov with Orano Med Theranostics, SAS as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1 Open-Label, First-in-human, Dose Escalation and Expansion Study to Determine the Safety, Tolerability, Dosimetry, Pharmacokinetics, and Preliminary Efficacy of 212Pb-DOTAM-GRPR1 in Adult Participants With Recurrent or Metastatic GRPR-expressing Tumors
Lead sponsor
Orano Med Theranostics, SAS
Phase
Phase 1
Overall status
Recruiting
Start date
December 22, 2022
Completion date
May 31, 2032
Enrollment
48 (estimated)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

breast cancer, cervical cancer, colon cancer, glioblastoma, mcrpc (metastatic castration-resistant prostate cancer), nonsmall cell lung cancer, nsclc