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Clinical trial

A Randomized Surgical Window of Opportunity Study With Dose Escalation to Evaluate Whether Oral Fluoxetine Can Induce Cytotoxic Lysosomal Stress and Enhance Temozolomide Efficacy in Clinical Glioma

NCT05634707 is registered in ClinicalTrials.gov with Duke University as lead sponsor.

NCT NCT05634707
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Registry record

As filed in ClinicalTrials.gov.

Title
A Randomized Surgical Window of Opportunity Study With Dose Escalation to Evaluate Whether Oral Fluoxetine Can Induce Cytotoxic Lysosomal Stress and Enhance Temozolomide Efficacy in Clinical Glioma
Lead sponsor
Duke University
Phase
Phase 1
Overall status
Active, not recruiting
Start date
August 5, 2023
Completion date
June 5, 2027
Enrollment
10 (actual)
Sites
4

Conditions

As the registry lists them; a condition with its own page is linked.

brain tumor, recurrent, primary brain tumor