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Clinical trial

International Proof of Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory HEMatological Malignancies in Children, Subprotocol D: Trametinib + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

NCT05658640 is registered in ClinicalTrials.gov with Princess Maxima Center for Pediatric Oncology as lead sponsor.

NCT NCT05658640
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Registry record

As filed in ClinicalTrials.gov.

Title
International Proof of Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory HEMatological Malignancies in Children, Subprotocol D: Trametinib + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Lead sponsor
Princess Maxima Center for Pediatric Oncology
Phase
Phase 1/2
Overall status
Recruiting
Start date
November 14, 2023
Completion date
April 1, 2029
Enrollment
26 (estimated)
Sites
36

Conditions

As the registry lists them; a condition with its own page is linked.

acute lymphoblastic leukemia, in relapse, lymphoblastic lymphoma (precursor b-lymphoblastic lymphoma/leukaemia) recurrent, lymphoblastic lymphoma (precursor b-lymphoblastic lymphoma/leukaemia) refractory, lymphoblastic lymphoma (precursor t-lymphoblastic lymphoma/leukaemia) recurrent, lymphoblastic lymphoma (precursor t-lymphoblastic lymphoma/leukaemia) refractory