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Clinical trial

A Phase Ib/II Open Label, Multi-arm, Parallel Cohort Dose Finding and Expansion Study to Assess the Safety, Pharmacokinetics and Efficacy of NUC-3373, a Nucleotide Analogue, Given in Combination With Standard Approved Agents in Patients With Advanced Solid Tumours

NCT05714553 is registered in ClinicalTrials.gov with NuCana plc as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase Ib/II Open Label, Multi-arm, Parallel Cohort Dose Finding and Expansion Study to Assess the Safety, Pharmacokinetics and Efficacy of NUC-3373, a Nucleotide Analogue, Given in Combination With Standard Approved Agents in Patients With Advanced Solid Tumours
Lead sponsor
NuCana plc
Phase
Phase 1/2
Overall status
Terminated
Start date
March 8, 2023
Completion date
May 30, 2025
Enrollment
19 (actual)
Sites
4

Conditions

As the registry lists them; a condition with its own page is linked.

advanced cancer, advanced solid tumor, classical hodgkin lymphoma, endometrial carcinoma, gastric cancer, head and neck squamous cell carcinoma, melanoma, metastatic cancer, msi-h colorectal cancer, neoplasm malignant, non small cell lung cancer, oesophageal carcinoma, pleural mesothelioma, renal cell carcinoma, subungual squamous cell carcinoma, triple negative breast cancer, urothelial carcinoma