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Condition (MeSH)

Carcinoma, Transitional Cell

ClinicalTrials.gov lists 617 trials for Carcinoma, Transitional Cell or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 23.

MeSH D002295 Neoplasms Neoplasm C04
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Phase 1 Phase 1 142 Phase 1/2 Phase 1/2 76 Phase 2 Phase 2 198 Phase 2/3 Phase 2/3 9 Phase 3 Phase 3 39 Phase 4 Phase 4 3 Not applicable Not applicable 40 Observational Observational 105 Phase 1 Phase 1 142 Phase 1/2 Phase 1/2 76 Phase 2 Phase 2 198 Phase 2/3 Phase 2/3 9 Phase 3 Phase 3 39 Phase 4 Phase 4 3 Not applicable Not applicable 40 Observational Observational 105

Trials per phase (log scale)

1 more section with rows

617 of the 617 trials are tagged with Carcinoma, Transitional Cell itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Carcinoma, Transitional Cell trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access)

Top of scale: 60

1994: 1 trials (Phase 1 1) 2000: 3 trials (Phase 3 1, Phase 2 2) 2002: 1 trials (Phase 2 1) 2003: 2 trials (Phase 2 1, Phase 1 1) 2004: 5 trials (Observational 1, Phase 2 3, Phase 1/2 1) 2005: 5 trials (Observational 1, Phase 3 1, Phase 2 2, Phase 1 1) 2006: 6 trials (Phase 2/3 1, Phase 2 3, Phase 1/2 2) 2007: 6 trials (Not applicable 1, Phase 2/3 1, Phase 2 1, Phase 1 3) 2008: 10 trials (Observational 1, Not applicable 1, Phase 2 8) 2009: 3 trials (Observational 1, Phase 3 1, Phase 2 1) 2010: 11 trials (Observational 2, Not applicable 1, Phase 3 1, Phase 2 5, Phase 1/2 1, Phase 1 1) 2011: 11 trials (Observational 3, Not applicable 1, Phase 3 1, Phase 2 4, Phase 1 2) 2012: 13 trials (Observational 2, Phase 2 7, Phase 1/2 1, Phase 1 3) 2013: 6 trials (Observational 1, Phase 2/3 1, Phase 2 3, Phase 1 1) 2014: 10 trials (Observational 1, Not applicable 1, Phase 2/3 1, Phase 2 5, Phase 1/2 1, Phase 1 1) 2015: 18 trials (Other 1, Observational 1, Phase 3 2, Phase 2 6, Phase 1/2 3, Phase 1 5) 2016: 25 trials (Observational 5, Not applicable 3, Phase 3 3, Phase 2 6, Phase 1/2 3, Phase 1 5) 2017: 48 trials (Observational 5, Not applicable 4, Phase 3 4, Phase 2 18, Phase 1/2 9, Phase 1 8) 2018: 46 trials (Observational 4, Not applicable 2, Phase 2/3 1, Phase 2 16, Phase 1/2 8, Phase 1 15) 2019: 60 trials (Observational 10, Not applicable 5, Phase 3 4, Phase 2 17, Phase 1/2 9, Phase 1 15) 2020: 47 trials (Observational 8, Not applicable 2, Phase 4 1, Phase 3 1, Phase 2 13, Phase 1/2 6, Phase 1 16) 2021: 50 trials (Observational 8, Not applicable 3, Phase 3 3, Phase 2 14, Phase 1/2 9, Phase 1 13) 2022: 43 trials (Observational 9, Not applicable 1, Phase 4 1, Phase 3 5, Phase 2 13, Phase 1/2 7, Phase 1 7) 2023: 47 trials (Observational 10, Not applicable 5, Phase 3 2, Phase 2 15, Phase 1/2 6, Phase 1 9) 2024: 37 trials (Observational 10, Not applicable 1, Phase 3 2, Phase 2/3 1, Phase 2 9, Phase 1/2 4, Phase 1 10) 2025: 46 trials (Observational 11, Not applicable 5, Phase 4 1, Phase 3 4, Phase 2/3 2, Phase 2 11, Phase 1/2 2, Phase 1 10)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 53
2025 46
2024 37
2023 47
2022 43
2021 50
2020 47
2019 60
2018 46
2017 48

Forecast of the full-year count, planned starts included, not rows of this table: about 65 trials starting in 2026 and about 52 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 120 trials still running at the 2026-10-09 snapshot; registered median of 33 months across 309 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Carcinoma, Transitional Cell trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 142
Phase 1/2 76
Phase 2 198
Phase 2/3 9
Phase 3 39
Phase 4 3
Not applicable 40
Observational 105
Expanded access 5

How many Carcinoma, Transitional Cell trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 23
Recruiting 132
Enrolling by invitation 4
Active, not recruiting 76
Available 3

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Carcinoma, Transitional Cell trials? (8)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 23
Pfizer 10
UroGen Pharma Ltd. 10
Bristol-Myers Squibb 8
Hoffmann-La Roche 8

Which drugs are being tested for Carcinoma, Transitional Cell? (7)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
PEMBROLIZUMAB 87
NIVOLUMAB 40
Enfortumab Vedotin 29
Avelumab 23
IPILIMUMAB 15

Interventions as named in the registry (8)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Gemcitabine/Gemzar 47
Cisplatin 1 31
Atezolizumab SC 30
or carboplatin 25
Docetetaxel 21

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Carcinoma, Transitional Cell trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Urinary tract infection 431 37
Disease progression 305 12
Pneumonia 235 38
Fatigue 227 31
Acute kidney injury 226 31

Which publications cover Carcinoma, Transitional Cell? (549)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages