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Clinical trial

A Randomized Open-label Phase 2 Study of TALazoparib With or Without ENzaluTamide in Patients With Metastatic Castration-Resistant Prostate Cancer and HRR Mutations After Progression on Abiraterone Acetate or Darolutamide

NCT06844383 is registered in ClinicalTrials.gov with Prostate Cancer Clinical Trials Consortium as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Randomized Open-label Phase 2 Study of TALazoparib With or Without ENzaluTamide in Patients With Metastatic Castration-Resistant Prostate Cancer and HRR Mutations After Progression on Abiraterone Acetate or Darolutamide
Lead sponsor
Prostate Cancer Clinical Trials Consortium
Phase
Phase 2
Overall status
Recruiting
Start date
May 4, 2026
Completion date
March 31, 2030
Enrollment
126 (estimated)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

mcrpc (metastatic castration-resistant prostate cancer), prostate cancer (adenocarcinoma)