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Clinical trial

Feasibility of Treating Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma With Zanubrutinib in Combination With the BCL2 Inhibitor, Sonrotoclax, Focusing on Access for Underrepresented Ethnic/Racial Minorities

NCT06859008 is registered in ClinicalTrials.gov with City of Hope Medical Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Feasibility of Treating Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma With Zanubrutinib in Combination With the BCL2 Inhibitor, Sonrotoclax, Focusing on Access for Underrepresented Ethnic/Racial Minorities
Lead sponsor
City of Hope Medical Center
Phase
Phase 1
Overall status
Recruiting
Start date
August 25, 2025
Completion date
January 31, 2029
Enrollment
37 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

chronic lymphocytic leukemia/small lymphocytic lymphoma, recurrent chronic lymphocytic leukemia/small lymphocytic lymphoma, recurrent diffuse large b-cell lymphoma, recurrent extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue, recurrent grade 1 follicular lymphoma, recurrent grade 2 follicular lymphoma, recurrent grade 3a follicular lymphoma, recurrent mantle cell lymphoma, recurrent nodal marginal zone lymphoma, recurrent splenic marginal zone lymphoma, refractory chronic lymphocytic leukemia/small lymphocytic lymphoma, refractory diffuse large b-cell lymphoma, refractory extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue, refractory grade 1 follicular lymphoma, refractory grade 2 follicular lymphoma, refractory grade 3a follicular lymphoma, refractory mantle cell lymphoma, refractory nodal marginal zone lymphoma, refractory splenic marginal zone lymphoma