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Clinical trial

A Phase 1/2, First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors

NCT07038343 is registered in ClinicalTrials.gov with Avenzo Therapeutics, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1/2, First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors
Lead sponsor
Avenzo Therapeutics, Inc.
Phase
Phase 1/2
Overall status
Recruiting
Start date
June 4, 2025
Completion date
December 31, 2030
Enrollment
480 (estimated)
Sites
19

Conditions

As the registry lists them; a condition with its own page is linked.

biliary tract cancer (btc), epithelial tumor, locally advanced, lung cancers, metastatic solid tumors, nasopharyngeal cancers, solid tumor cancer, urothelial cancer