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Clinical trial

A Phase II, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Metyrapone in Subjects Diagnosed With Mild Autonomous Cortisol Secretion (MACS)

NCT07138274 is registered in ClinicalTrials.gov with Mayo Clinic as lead sponsor.

NCT NCT07138274
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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase II, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Metyrapone in Subjects Diagnosed With Mild Autonomous Cortisol Secretion (MACS)
Lead sponsor
Mayo Clinic
Phase
Phase 2
Overall status
Recruiting
Start date
October 31, 2026
Completion date
December 31, 2031
Enrollment
90 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

autonomous cortisol secretion (acs), mild autonomous cortisol secretion (macs)