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Clinical trial

Phase I Trial of ATR Inhibitor Camonsertib Combined With Stereotactic Body Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

NCT07156227 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

NCT NCT07156227
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Registry record

As filed in ClinicalTrials.gov.

Title
Phase I Trial of ATR Inhibitor Camonsertib Combined With Stereotactic Body Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Recruiting
Start date
February 13, 2027
Completion date
May 31, 2029
Enrollment
39 (estimated)
Sites
3

Conditions

As the registry lists them; a condition with its own page is linked.

clinical stage iii hpv-mediated (p16-positive) oropharyngeal carcinoma ajcc v8, recurrent head and neck squamous cell carcinoma, recurrent hypopharyngeal squamous cell carcinoma, recurrent laryngeal squamous cell carcinoma, recurrent oral cavity squamous cell carcinoma, recurrent oropharyngeal squamous cell carcinoma, recurrent paranasal sinus squamous cell carcinoma, stage iii head and neck cutaneous squamous cell carcinoma ajcc v8, stage iii hypopharyngeal carcinoma ajcc v8, stage iii laryngeal cancer ajcc v8, stage iii lip and oral cavity cancer ajcc v8, stage iii oropharyngeal (p16-negative) carcinoma ajcc v8, stage iii sinonasal cancer ajcc v8, stage iv head and neck cutaneous squamous cell carcinoma ajcc v8, stage iva hypopharyngeal carcinoma ajcc v8, stage iva laryngeal cancer ajcc v8, stage iva lip and oral cavity cancer ajcc v8, stage iva oropharyngeal (p16-negative) carcinoma ajcc v8, stage iva sinonasal cancer ajcc v8, stage ivb hypopharyngeal carcinoma ajcc v8, stage ivb laryngeal cancer ajcc v8, stage ivb lip and oral cavity cancer ajcc v8, stage ivb oropharyngeal (p16-negative) carcinoma ajcc v8, stage ivb sinonasal cancer ajcc v8, unresectable head and neck squamous cell carcinoma, unresectable hypopharyngeal squamous cell carcinoma, unresectable laryngeal squamous cell carcinoma, unresectable oral cavity squamous cell carcinoma, unresectable oropharyngeal squamous cell carcinoma, unresectable paranasal sinus squamous cell carcinoma