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Clinical trial

KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use (KIPRUN) - Protocol for a Multi-center, Randomized, Superiority Trial to Compare the Efficacy and Safety of Procalcitonin Kinetics-guided and Absolute Procalcitonin Value-guided Antibiotic Initiation in Reducing Unnecessary Antibiotic Therapy in Critically Ill Patients

NCT07211620 is registered in ClinicalTrials.gov with Semmelweis University as lead sponsor.

NCT NCT07211620
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Registry record

As filed in ClinicalTrials.gov.

Title
KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use (KIPRUN) - Protocol for a Multi-center, Randomized, Superiority Trial to Compare the Efficacy and Safety of Procalcitonin Kinetics-guided and Absolute Procalcitonin Value-guided Antibiotic Initiation in Reducing Unnecessary Antibiotic Therapy in Critically Ill Patients
Lead sponsor
Semmelweis University
Phase
Not applicable
Overall status
Recruiting
Start date
November 6, 2025
Completion date
December 31, 2027
Enrollment
250 (estimated)
Sites
2

Conditions

As the registry lists them; a condition with its own page is linked.

infection, sepsis