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Clinical trial

Investigator-Initiated, Open-Label, Phase II Trial of Selinexor in Combination With Pacritinib in Patients With Myelofibrosis Who Are JAK Inhibitor-Naïve and Have Cytopenias (ILLUMINATE)

NCT07447817 is registered in ClinicalTrials.gov with John Mascarenhas as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Investigator-Initiated, Open-Label, Phase II Trial of Selinexor in Combination With Pacritinib in Patients With Myelofibrosis Who Are JAK Inhibitor-Naïve and Have Cytopenias (ILLUMINATE)
Lead sponsor
John Mascarenhas
Phase
Phase 2
Overall status
Not yet recruiting
Start date
May 4, 2026
Completion date
May 24, 2030
Enrollment
26 (estimated)
Sites
3

Conditions

As the registry lists them; a condition with its own page is linked.

myelofibrosis, post-essential thrombocythemia myelofibrosis, post-polycythemia vera myelofibrosis