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Clinical trial

A Safety and Feasibility Study of NeuroNavigation-Guided Low Intensity Focused Ultrasound With Microbubbles to Enhance Nivolumab Delivery for the Treatment of Relapsed and Progressive Diffuse Midline Glioma and Other High Grade Brain Tumors

NCT07664176 is registered in ClinicalTrials.gov with Children's National Research Institute as lead sponsor.

NCT NCT07664176
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Registry record

As filed in ClinicalTrials.gov.

Title
A Safety and Feasibility Study of NeuroNavigation-Guided Low Intensity Focused Ultrasound With Microbubbles to Enhance Nivolumab Delivery for the Treatment of Relapsed and Progressive Diffuse Midline Glioma and Other High Grade Brain Tumors
Lead sponsor
Children's National Research Institute
Phase
Phase 1
Overall status
Recruiting
Start date
September 30, 2026
Completion date
December 31, 2030
Enrollment
30 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

atypical teratoid/rhabdoid tumor (atrt) of the cns, brain tumor recurrent, diffuse midline glioma or diffuse intrinsic pontine glioma, ependymoma recurrent, high grade gliomas, medulloblastoma recurrent