Condition (MeSH)
Morton Neuroma
ClinicalTrials.gov lists 25 trials for Morton Neuroma or a narrower condition beneath it. Centrexion Therapeutics has the most among industry and government lead sponsors, with 3.
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Trials per phase
25 of the 25 trials are tagged with Morton Neuroma itself; the rest are tagged with a narrower condition beneath it.
When did Morton Neuroma trials start? (13)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 4
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 1 |
| 2022 | 5 |
| 2021 | 2 |
| 2018 | 2 |
| 2016 | 2 |
| 2015 | 2 |
| 2014 | 3 |
| 2012 | 1 |
| 2011 | 1 |
Showing 10 of 13 earlier years.
No forecast is made for this condition: it averages 1.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Morton Neuroma trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 4 |
| Phase 4 | 1 |
| Not applicable | 13 |
| Observational | 3 |
How many Morton Neuroma trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 1 |
| Enrolling by invitation | 1 |
| Completed | 15 |
| Withdrawn | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Morton Neuroma trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Centrexion Therapeutics | 3 |
| AlgoRx Pharmaceuticals | 1 |
| AstraZeneca | 1 |
| Axogen Corporation | 1 |
| National Institutes of Health Clinical Center (CC) | 1 |
Which drugs are being tested for Morton Neuroma? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Resiniferatoxin | 1 |
| Scandicaine | 1 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Capsaicin 8% | 3 |
| Cryoablation | 2 |
| L:Lidocaine | 2 |
| NAC 0mg/day (Placebo) | 1 |
| Injection of Steroid into Foot | 1 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Morton Neuroma trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| ABORTION SPONTANEOUS | 1 | 1 |
| ACUTE MYOCARDIAL INFARCTION | 1 | 1 |
| APPENDICITIS | 1 | 1 |
| CEREBROVASCULAR ACCIDENT | 1 | 1 |
| COVID-19 PNEUMONIA | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Morton Neuroma? (5)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Ultrasound-Guided Injection Treatments Versus Surgical Neurectomy for Morton Neuroma: A Cost-Effectiveness Analysis. | AJR. American journal of roentgenology | 2022 | Yes |
| Non-surgical treatments for Morton's neuroma: A systematic review. | Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons | 2020 | Yes |
| The effectiveness of non-surgical interventions for common plantar digital compressive neuropathy (Morton's neuroma): a systematic review and meta-analysis. | Journal of foot and ankle research | 2019 | Yes |
| A randomized, double-blind, placebo-controlled trial of injected capsaicin for pain in Morton's neuroma. | Pain | 2016 | Yes |
| US of the Peripheral Nerves of the Lower Extremity: A Landmark Approach. | Radiographics : a review publication of the Radiological Society of North America, Inc | 2016 | No |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.