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Condition (MeSH)

Urinary Bladder Neoplasms

ClinicalTrials.gov lists 1,854 trials for Urinary Bladder Neoplasms or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 66.

MeSH D001749 Neoplasms Neoplasm C04 C12
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Phase 1 Phase 1 279 Phase 1/2 Phase 1/2 135 Phase 2 Phase 2 411 Phase 2/3 Phase 2/3 24 Phase 3 Phase 3 164 Phase 4 Phase 4 34 Not applicable Not applicable 383 Observational Observational 417 Phase 1 Phase 1 279 Phase 1/2 Phase 1/2 135 Phase 2 Phase 2 411 Phase 2/3 Phase 2/3 24 Phase 3 Phase 3 164 Phase 4 Phase 4 34 Not applicable Not applicable 383 Observational Observational 417

Trials per phase

1 more section with rows

1,719 of the 1,854 trials are tagged with Urinary Bladder Neoplasms itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Urinary Bladder Neoplasms trials start? (36)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 7 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access)

Top of scale: 144

1990: 1 trials (Not applicable 1) 1991: 1 trials (Phase 3 1) 1993: 1 trials (Phase 2/3 1) 1994: 5 trials (Observational 1, Phase 3 2, Phase 2/3 1, Phase 1 1) 1995: 2 trials (Phase 2/3 1, Phase 2 1) 1996: 6 trials (Phase 3 1, Phase 2 3, Phase 1/2 1, Phase 1 1) 1997: 9 trials (Observational 1, Phase 3 2, Phase 2 2, Phase 1/2 2, Phase 1 2) 1998: 17 trials (Observational 3, Phase 3 4, Phase 2 7, Phase 1 3) 1999: 17 trials (Observational 2, Phase 3 4, Phase 2 6, Phase 1/2 1, Phase 1 4) 2000: 19 trials (Observational 1, Not applicable 1, Phase 3 2, Phase 2/3 1, Phase 2 8, Phase 1 6) 2001: 20 trials (Phase 3 5, Phase 2/3 1, Phase 2 8, Phase 1/2 1, Phase 1 5) 2002: 13 trials (Observational 4, Not applicable 1, Phase 3 3, Phase 2 4, Phase 1 1) 2003: 21 trials (Observational 1, Not applicable 1, Phase 2 14, Phase 1 5) 2004: 29 trials (Observational 5, Not applicable 3, Phase 3 2, Phase 2 9, Phase 1/2 4, Phase 1 6) 2005: 34 trials (Observational 9, Not applicable 4, Phase 3 6, Phase 2 8, Phase 1/2 3, Phase 1 4) 2006: 28 trials (Observational 2, Not applicable 3, Phase 4 1, Phase 2/3 1, Phase 2 11, Phase 1/2 3, Phase 1 7) 2007: 37 trials (Observational 6, Not applicable 3, Phase 4 2, Phase 3 7, Phase 2/3 1, Phase 2 12, Phase 1 6) 2008: 42 trials (Observational 11, Not applicable 4, Phase 4 1, Phase 3 1, Phase 2 18, Phase 1/2 2, Phase 1 5) 2009: 41 trials (Observational 7, Not applicable 7, Phase 3 4, Phase 2/3 2, Phase 2 13, Phase 1/2 3, Phase 1 5) 2010: 28 trials (Observational 4, Not applicable 3, Phase 3 4, Phase 2 9, Phase 1/2 3, Phase 1 5) 2011: 39 trials (Observational 4, Not applicable 8, Phase 3 2, Phase 2/3 1, Phase 2 12, Phase 1/2 3, Phase 1 9) 2012: 40 trials (Observational 5, Not applicable 10, Phase 3 5, Phase 2 9, Phase 1/2 4, Phase 1 7) 2013: 48 trials (Other 1, Observational 10, Not applicable 14, Phase 4 2, Phase 3 2, Phase 2/3 2, Phase 2 6, Phase 1/2 4, Phase 1 7) 2014: 62 trials (Observational 13, Not applicable 18, Phase 4 1, Phase 3 4, Phase 2/3 1, Phase 2 16, Phase 1/2 4, Phase 1 5) 2015: 70 trials (Observational 12, Not applicable 18, Phase 4 2, Phase 3 6, Phase 2/3 1, Phase 2 13, Phase 1/2 5, Phase 1 13) 2016: 77 trials (Observational 18, Not applicable 19, Phase 4 1, Phase 3 8, Phase 2 10, Phase 1/2 5, Phase 1 16) 2017: 92 trials (Observational 24, Not applicable 18, Phase 4 9, Phase 3 5, Phase 2/3 1, Phase 2 17, Phase 1/2 4, Phase 1 14) 2018: 96 trials (Observational 14, Not applicable 26, Phase 4 1, Phase 3 8, Phase 2/3 1, Phase 2 29, Phase 1/2 6, Phase 1 11) 2019: 105 trials (Observational 24, Not applicable 20, Phase 4 2, Phase 3 10, Phase 2 18, Phase 1/2 12, Phase 1 19) 2020: 113 trials (Observational 36, Not applicable 24, Phase 4 1, Phase 3 6, Phase 2 23, Phase 1/2 5, Phase 1 18) 2021: 144 trials (Observational 47, Not applicable 28, Phase 4 2, Phase 3 11, Phase 2 24, Phase 1/2 18, Phase 1 14) 2022: 109 trials (Observational 35, Not applicable 23, Phase 4 2, Phase 3 6, Phase 2 16, Phase 1/2 11, Phase 1 16) 2023: 129 trials (Observational 40, Not applicable 37, Phase 4 1, Phase 3 10, Phase 2/3 1, Phase 2 20, Phase 1/2 4, Phase 1 16) 2024: 112 trials (Observational 29, Not applicable 31, Phase 4 2, Phase 3 7, Phase 2/3 1, Phase 2 15, Phase 1/2 8, Phase 1 19) 2025: 127 trials (Observational 30, Not applicable 31, Phase 4 3, Phase 3 11, Phase 2/3 4, Phase 2 23, Phase 1/2 11, Phase 1 14)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 100
2025 127
2024 112
2023 129
2022 109
2021 144
2020 113
2019 105
2018 96
2017 92

Forecast of the full-year count, planned starts included, not rows of this table: about 120 trials starting in 2026 and about 120 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 261 trials still running at the 2026-10-09 snapshot; registered median of 36 months across 976 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Urinary Bladder Neoplasms trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 279
Phase 1/2 135
Phase 2 411
Phase 2/3 24
Phase 3 164
Phase 4 34
Not applicable 383
Observational 417
Expanded access 7

How many Urinary Bladder Neoplasms trials are recruiting? (12)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 85
Recruiting 319
Enrolling by invitation 11
Active, not recruiting 158
Available 4

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Urinary Bladder Neoplasms trials? (8)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 66
AstraZeneca 19
Merck Sharp & Dohme LLC 18
Eli Lilly and Company 16
Pfizer 15

Which drugs are being tested for Urinary Bladder Neoplasms? (6)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
PEMBROLIZUMAB 76
(nab)-paclitaxel 40
NIVOLUMAB 36
DURVALUMAB 31
Enfortumab Vedotin 26

Interventions as named in the registry (9)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Gemcitabine/Gemzar 146
Cisplatin 1 102
Mitomycin C 0.02% 45
or carboplatin 39
Docetetaxel 37

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Urinary Bladder Neoplasms trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Urinary tract infection 645 61
Pneumonia 409 55
Sepsis 402 85
Acute kidney injury 374 52
Disease progression 301 12

Which publications cover Urinary Bladder Neoplasms? (1,377)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages