Condition (MeSH)
Botulism
ClinicalTrials.gov lists 19 trials for Botulism or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 3.
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Trials per phase
19 of the 19 trials are tagged with Botulism itself; the rest are tagged with a narrower condition beneath it.
When did Botulism trials start? (13)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2024 | 2 |
| 2023 | 2 |
| 2020 | 2 |
| 2019 | 1 |
| 2018 | 1 |
| 2017 | 1 |
| 2016 | 1 |
| 2014 | 2 |
| 2013 | 1 |
| 2011 | 2 |
Showing 10 of 13 earlier years.
No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Botulism trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 5 |
| Phase 1/2 | 1 |
| Phase 2 | 3 |
| Phase 2/3 | 1 |
| Phase 3 | 2 |
| Phase 4 | 1 |
| Not applicable | 1 |
| Observational | 5 |
How many Botulism trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 1 |
| Enrolling by invitation | 1 |
| Completed | 14 |
| Withdrawn | 1 |
| Unknown status | 2 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Botulism trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | 3 |
| Department of Medical Services Ministry of Public Health of Thailand | 2 |
| Emergent BioSolutions | 2 |
| Alachua Government Services, Inc. | 1 |
| DynPort Vaccine Company LLC, A GDIT Company | 1 |
Which drugs are being tested for Botulism? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| 3, 4-Diaminopyridine | 2 |
| Botulinum Toxin | 2 |
| BOTULINUM NEUROTOXIN TYPE-A | 1 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Ribavirine | 4 |
| Botulinum AntiToxin | 2 |
| NTM-1632 | 1 |
| Standard-of-care corticosteroid injections | 1 |
| NTM-1633 | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Botulism trials report? (1)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| pulmonary embolism | 1 | 1 |
Which publications cover Botulism? (22)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 22 publications.
Prevalence (75)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Botulism | Annual incidence | <1 / 1 000 000 | United Kingdom | GB | Exact |
| Botulism | Annual incidence | <1 / 1 000 000 | United Kingdom | GB | Unspecified |
| Botulism | Annual incidence | <1 / 1 000 000 | United Kingdom | GB | Exact |
| Botulism | Annual incidence | 1-9 / 1 000 000 | United States | US | Exact |
| Botulism | Annual incidence | 1-9 / 1 000 000 | United States | US | Exact |
Showing 5 of 75 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Botulism | 1267 | Exact | Orphadata Science knowledge files, Product 1 |
| Botulism | 1267 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.