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Condition (MeSH)

Clostridium Infections

ClinicalTrials.gov lists 602 trials for Clostridium Infections or a narrower condition beneath it. GlaxoSmithKline has the most among industry and government lead sponsors, with 104.

MeSH D003015 Infections C01
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Phase 1 Phase 1 54 Phase 1/2 Phase 1/2 16 Phase 2 Phase 2 81 Phase 2/3 Phase 2/3 15 Phase 3 Phase 3 179 Phase 4 Phase 4 85 Not applicable Not applicable 67 Observational Observational 103 Phase 1 Phase 1 54 Phase 1/2 Phase 1/2 16 Phase 2 Phase 2 81 Phase 2/3 Phase 2/3 15 Phase 3 Phase 3 179 Phase 4 Phase 4 85 Not applicable Not applicable 67 Observational Observational 103

Trials per phase

1 more section with rows

244 of the 602 trials are tagged with Clostridium Infections itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Clostridium Infections trials start? (30)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 44

1997: 3 trials (Phase 3 2, Phase 1 1) 1998: 2 trials (Not applicable 1, Phase 2 1) 1999: 3 trials (Not applicable 1, Phase 3 1, Phase 2 1) 2000: 6 trials (Observational 1, Not applicable 3, Phase 3 2) 2001: 1 trials (Phase 3 1) 2002: 6 trials (Phase 3 3, Phase 2 3) 2003: 15 trials (Observational 3, Phase 4 4, Phase 3 6, Phase 2 2) 2004: 11 trials (Observational 1, Phase 4 3, Phase 3 6, Phase 2 1) 2005: 25 trials (Observational 4, Phase 4 3, Phase 3 12, Phase 2 3, Phase 1 3) 2006: 44 trials (Observational 5, Phase 4 5, Phase 3 28, Phase 2 5, Phase 1 1) 2007: 21 trials (Observational 2, Not applicable 1, Phase 4 4, Phase 3 14) 2008: 16 trials (Observational 2, Phase 4 8, Phase 3 4, Phase 2 2) 2009: 17 trials (Observational 2, Not applicable 1, Phase 4 3, Phase 3 7, Phase 2 3, Phase 1 1) 2010: 25 trials (Observational 3, Not applicable 2, Phase 4 3, Phase 3 7, Phase 2/3 1, Phase 2 8, Phase 1 1) 2011: 30 trials (Observational 3, Phase 4 9, Phase 3 13, Phase 2/3 1, Phase 2 3, Phase 1 1) 2012: 27 trials (Observational 4, Not applicable 4, Phase 4 8, Phase 3 5, Phase 2 1, Phase 1/2 1, Phase 1 4) 2013: 32 trials (Observational 5, Not applicable 6, Phase 4 3, Phase 3 9, Phase 2 4, Phase 1/2 1, Phase 1 4) 2014: 24 trials (Observational 4, Not applicable 2, Phase 4 4, Phase 3 8, Phase 2/3 1, Phase 2 4, Phase 1 1) 2015: 26 trials (Observational 7, Not applicable 4, Phase 4 1, Phase 3 5, Phase 2/3 1, Phase 2 6, Phase 1/2 1, Phase 1 1) 2016: 26 trials (Observational 4, Not applicable 4, Phase 4 6, Phase 3 4, Phase 2/3 1, Phase 2 2, Phase 1/2 1, Phase 1 4) 2017: 28 trials (Observational 6, Not applicable 4, Phase 4 3, Phase 3 6, Phase 2/3 1, Phase 2 1, Phase 1/2 4, Phase 1 3) 2018: 26 trials (Observational 6, Not applicable 6, Phase 4 4, Phase 3 3, Phase 2/3 2, Phase 2 4, Phase 1 1) 2019: 35 trials (Observational 8, Not applicable 4, Phase 4 3, Phase 3 5, Phase 2 11, Phase 1/2 2, Phase 1 2) 2020: 19 trials (Observational 7, Not applicable 3, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 4, Phase 1 2) 2021: 19 trials (Observational 4, Not applicable 5, Phase 4 2, Phase 3 5, Phase 2 2, Phase 1 1) 2022: 14 trials (Observational 2, Not applicable 1, Phase 4 1, Phase 3 5, Phase 2 3, Phase 1/2 1, Phase 1 1) 2023: 23 trials (Observational 3, Not applicable 5, Phase 4 1, Phase 3 6, Phase 2 1, Phase 1/2 1, Phase 1 6) 2024: 25 trials (Observational 4, Not applicable 4, Phase 4 1, Phase 3 5, Phase 2/3 3, Phase 2 3, Phase 1/2 2, Phase 1 3) 2025: 16 trials (Observational 3, Not applicable 1, Phase 4 1, Phase 3 1, Phase 2/3 2, Phase 2 2, Phase 1/2 1, Phase 1 5)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 29
2025 16
2024 25
2023 23
2022 14
2021 19
2020 19
2019 35
2018 26
2017 28

Forecast of the full-year count, planned starts included, not rows of this table: about 33 trials starting in 2026 and about 23 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 31 months from start to primary completion across 29 trials still running at the 2026-10-09 snapshot; registered median of 16 months across 437 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Clostridium Infections trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 54
Phase 1/2 16
Phase 2 81
Phase 2/3 15
Phase 3 179
Phase 4 85
Not applicable 67
Observational 103
Expanded access 2

How many Clostridium Infections trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 24
Recruiting 40
Enrolling by invitation 2
Active, not recruiting 10
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Clostridium Infections trials? (12)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
GlaxoSmithKline 104
Sanofi Pasteur, a Sanofi Company 60
Sanofi 21
National Institute of Allergy and Infectious Diseases (NIAID) 16
CanSino Biologics Inc. 10

Which drugs are being tested for Clostridium Infections? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Fidaxomicin 16
Fecal Microbiota 11
Bezlotoxumab 9
HIBERIX™ 8

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Vancomycin 1.1% 51
BOOSTRIX 19
Fecal Microbiota Transplantation 18
InfanrixTM hexa 18
Infanrix IPV Hib 8

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Clostridium Infections trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 533 67
Bronchiolitis 295 22
Gastroenteritis 246 49
Clostridium difficile infection 217 18
Sepsis 193 28

Which publications cover Clostridium Infections? (404)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (4)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages