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Condition (MeSH)

Cholera

ClinicalTrials.gov lists 76 trials for Cholera or a narrower condition beneath it. Bavarian Nordic has the most among industry and government lead sponsors, with 5.

MeSH D002771 Infections C01 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 6 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 18 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 16 Phase 4 Phase 4 9 Not applicable Not applicable 15 Observational Observational 9 Phase 1 Phase 1 6 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 18 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 16 Phase 4 Phase 4 9 Not applicable Not applicable 15 Observational Observational 9

Trials per phase

76 of the 76 trials are tagged with Cholera itself; the rest are tagged with a narrower condition beneath it.

Get the Cholera report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Cholera trials start? (25)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 8

2000: 1 trials (Phase 3 1) 2001: 1 trials (Phase 3 1) 2002: 1 trials (Phase 3 1) 2003: 1 trials (Phase 2 1) 2005: 2 trials (Phase 2 2) 2006: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 2007: 2 trials (Phase 3 1, Phase 2 1) 2008: 4 trials (Observational 1, Phase 2 1, Phase 1/2 1, Phase 1 1) 2009: 2 trials (Not applicable 2) 2010: 2 trials (Phase 2 2) 2011: 2 trials (Observational 1, Phase 2 1) 2012: 8 trials (Observational 1, Not applicable 1, Phase 4 3, Phase 3 1, Phase 1 2) 2013: 4 trials (Observational 2, Phase 3 1, Phase 1 1) 2014: 5 trials (Phase 4 1, Phase 3 2, Phase 2 2) 2015: 3 trials (Not applicable 1, Phase 3 1, Phase 2 1) 2016: 6 trials (Observational 1, Not applicable 2, Phase 3 1, Phase 2 1, Phase 1/2 1) 2017: 4 trials (Not applicable 1, Phase 4 2, Phase 2 1) 2018: 1 trials (Phase 2 1) 2019: 1 trials (Phase 2 1) 2021: 7 trials (Observational 2, Not applicable 2, Phase 3 2, Phase 2 1) 2022: 3 trials (Phase 4 1, Phase 3 1, Phase 1 1) 2023: 5 trials (Not applicable 1, Phase 4 1, Phase 3 2, Phase 2/3 1) 2024: 4 trials (Not applicable 3, Phase 2 1) 2025: 2 trials (Not applicable 1, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 2
2024 4
2023 5
2022 3
2021 7
2019 1
2018 1
2017 4
2016 6

No forecast is made for this condition: it averages 3.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 53 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Cholera trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 6
Phase 1/2 2
Phase 2 18
Phase 2/3 1
Phase 3 16
Phase 4 9
Not applicable 15
Observational 9

How many Cholera trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 9
Completed 54
Terminated 3
Withdrawn 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Cholera trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Bavarian Nordic 5
National Institute of Allergy and Infectious Diseases (NIAID) 3
Bharat Biotech International Limited 2
Sanofi Pasteur, a Sanofi Company 2

Which drugs are being tested for Cholera? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
VAXCHORA (Cholera Vaccine, Live, Oral) 5
iOWH032 3

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
ShanChol 8
1% Azithromycin 3
PXVX0200 3
Killed Bivalent (O1 and O139) whole cell oral cholera vaccine 3
PO ciprofloxacin 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Cholera trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Appendicitis 4 1
Pneumothorax 4 1
Convulsion 3 2
Kidney Infection 3 1
Pyelonephritis 3 2

Which publications cover Cholera? (99)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Prevalence (39)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Cholera Annual incidence <1 / 1 000 000 United Kingdom GB Exact
Cholera Annual incidence <1 / 1 000 000 United Kingdom GB Exact
Cholera Annual incidence <1 / 1 000 000 United Kingdom GB Unspecified
Cholera Point prevalence <1 / 1 000 000 United States US Exact
Cholera Point prevalence <1 / 1 000 000 United States US Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Cholera 173 Exact Orphanet Rare Disease Ontology (ORDO)
Cholera 173 Exact Orphadata Science knowledge files, Product 1

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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