Condition (MeSH)
Enterovirus Infections
ClinicalTrials.gov lists 463 trials for Enterovirus Infections or a narrower condition beneath it. GlaxoSmithKline has the most among industry and government lead sponsors, with 71.
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Trials per phase
1 more section with rows
47 of the 463 trials are tagged with Enterovirus Infections itself; the rest are tagged with a narrower condition beneath it.
When did Enterovirus Infections trials start? (30)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 34
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 13 |
| 2025 | 16 |
| 2024 | 20 |
| 2023 | 20 |
| 2022 | 11 |
| 2021 | 8 |
| 2020 | 17 |
| 2019 | 21 |
| 2018 | 27 |
| 2017 | 31 |
Showing 10 of 30 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 15 trials starting in 2026 and about 17 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 31 months from start to primary completion across 16 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 350 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Enterovirus Infections trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 34 |
| Phase 1/2 | 9 |
| Phase 2 | 49 |
| Phase 2/3 | 9 |
| Phase 3 | 133 |
| Phase 4 | 107 |
| Not applicable | 59 |
| Observational | 62 |
| Expanded access | 1 |
How many Enterovirus Infections trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 13 |
| Recruiting | 16 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 10 |
| Completed | 351 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Enterovirus Infections trials? (10)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| GlaxoSmithKline | 71 |
| Sanofi Pasteur, a Sanofi Company | 48 |
| Sinovac Biotech Co., Ltd | 45 |
| Centers for Disease Control and Prevention | 16 |
| Sanofi | 15 |
Showing 5 of 10 sponsors.
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| InfanrixTM hexa | 18 |
| Havrix+Havrix | 12 |
| EV71 Vaccine | 11 |
| IPV | 10 |
| Inactivated Poliomyelitis Vaccine | 9 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Enterovirus Infections trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Bronchiolitis | 337 | 29 |
| Pneumonia | 215 | 40 |
| Gastroenteritis | 197 | 34 |
| Febrile convulsion | 86 | 16 |
| Upper respiratory tract infection | 73 | 13 |
Showing 5 of 10 adverse events.
Which publications cover Enterovirus Infections? (60)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| EV68-228-N monoclonal antibody treatment halts progression of paralysis in a mouse model of EV-D68 induced acute flaccid myelitis. | mBio | 2025 | Yes |
| Respiratory virus coinfections with severe acute respiratory coronavirus virus 2 (SARS-CoV-2) continue to be rare one year into the coronavirus disease 2019 (COVID-19) pandemic in Alberta, Canada (June 2020-May 2021). | Infection control and hospital epidemiology | 2023 | Yes |
| Late-onset enteric virus infection associated with hepatitis (EVAH) in transplanted SCID patients. | The Journal of allergy and clinical immunology | 2023 | Yes |
| Prednisolone for the first rhinovirus induced wheezing reduces use of respiratory medication. | Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology | 2022 | Yes |
| Application of a VP4/VP2-inferred transmission clusters in estimating the impact of interventions on rhinovirus transmission. | Virology journal | 2022 | Yes |
Showing 5 of 60 publications.
Sub-conditions in MeSH (4)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.