Condition (MeSH)
Hearing Loss, Noise-Induced
ClinicalTrials.gov lists 45 trials for Hearing Loss, Noise-Induced or a narrower condition beneath it. Frequency Therapeutics has the most among industry and government lead sponsors, with 4.
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Trials per phase
45 of the 45 trials are tagged with Hearing Loss, Noise-Induced itself; the rest are tagged with a narrower condition beneath it.
When did Hearing Loss, Noise-Induced trials start? (19)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 6 |
| 2025 | 2 |
| 2024 | 1 |
| 2023 | 2 |
| 2022 | 3 |
| 2021 | 6 |
| 2020 | 4 |
| 2019 | 3 |
| 2018 | 1 |
| 2017 | 2 |
Showing 10 of 19 earlier years.
No forecast is made for this condition: it averages 3.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 34 months from start to primary completion across 5 trials still running at the 2026-10-09 snapshot; registered median of 14 months across 26 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Hearing Loss, Noise-Induced trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 4 |
| Phase 1/2 | 3 |
| Phase 2 | 9 |
| Phase 3 | 1 |
| Not applicable | 15 |
| Observational | 13 |
How many Hearing Loss, Noise-Induced trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 5 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 1 |
| Completed | 23 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Hearing Loss, Noise-Induced trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Frequency Therapeutics | 4 |
| Apple Inc. | 1 |
| Auris Medical AG | 1 |
| Edison Pharmaceuticals Inc | 1 |
| Gaziosmanpasa Research and Education Hospital | 1 |
Which drugs are being tested for Hearing Loss, Noise-Induced? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Ebselen | 1 |
| EPI-743 | 1 |
| OKN 007 | 1 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| FX-322 | 4 |
| Low dose zonisamide | 3 |
| Clemastine Fumarate Combined With Pink Noise | 1 |
| Investigational Regenerative Pharmacologic Therapy | 1 |
| N Acetylcysteine | 1 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Hearing Loss, Noise-Induced trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Brain Oedema | 2 | 1 |
| Encephalopathy | 2 | 2 |
| Aphasia | 1 | 1 |
| Cerebrial Infarction | 1 | 1 |
| Device-related infection | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Hearing Loss, Noise-Induced? (121)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Hyperbaric oxygen therapy and corticosteroids as combined treatment for acute acoustic trauma. | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery | 2025 | Yes |
| Hidden hearing loss: Fifteen years at a glance. | Hearing research | 2024 | Yes |
| Changing the Paradigm for School Hearing Screening Globally: Evaluation of Screening Protocols From Two Randomized Trials in Rural Alaska. | Ear and hearing | 2023 | Yes |
| Risk-taking propensity as a risk factor for noise-induced hearing loss in the general population. | International journal of audiology | 2023 | Yes |
| The effects of hearing protection devices on spatial awareness in complex listening environments. | PloS one | 2023 | Yes |
Showing 5 of 121 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.