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Condition (MeSH)

Hearing Loss, Sensorineural

ClinicalTrials.gov lists 461 trials for Hearing Loss, Sensorineural or a narrower condition beneath it. Cochlear has the most among industry and government lead sponsors, with 29.

MeSH D006319 Otorhinolaryngologic Diseases C09 C10 C23
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Phase 1 Phase 1 16 Phase 1/2 Phase 1/2 22 Phase 2 Phase 2 22 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 12 Phase 4 Phase 4 1 Not applicable Not applicable 251 Observational Observational 128 Phase 1 Phase 1 16 Phase 1/2 Phase 1/2 22 Phase 2 Phase 2 22 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 12 Phase 4 Phase 4 1 Not applicable Not applicable 251 Observational Observational 128

Trials per phase (log scale)

1 more section with rows

336 of the 461 trials are tagged with Hearing Loss, Sensorineural itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hearing Loss, Sensorineural trials start? (30)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 4 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 46

1993: 1 trials (Observational 1) 1998: 1 trials (Phase 3 1) 1999: 2 trials (Observational 2) 2000: 1 trials (Observational 1) 2001: 3 trials (Observational 3) 2002: 1 trials (Observational 1) 2003: 1 trials (Phase 2 1) 2004: 1 trials (Not applicable 1) 2005: 2 trials (Observational 2) 2006: 2 trials (Observational 2) 2007: 5 trials (Not applicable 5) 2008: 6 trials (Observational 1, Not applicable 2, Phase 2 2, Phase 1 1) 2009: 4 trials (Observational 2, Not applicable 2) 2010: 4 trials (Observational 2, Not applicable 2) 2011: 6 trials (Not applicable 3, Phase 3 1, Phase 1/2 1, Phase 1 1) 2012: 9 trials (Not applicable 4, Phase 3 1, Phase 2 1, Phase 1/2 2, Phase 1 1) 2013: 10 trials (Observational 2, Not applicable 3, Phase 3 2, Phase 2 1, Phase 1/2 1, Phase 1 1) 2014: 8 trials (Observational 5, Not applicable 1, Phase 2 1, Phase 1 1) 2015: 14 trials (Other 1, Observational 2, Not applicable 8, Phase 3 1, Phase 2 1, Phase 1/2 1) 2016: 15 trials (Other 1, Observational 1, Not applicable 10, Phase 3 1, Phase 2/3 2) 2017: 19 trials (Other 1, Observational 6, Not applicable 9, Phase 3 1, Phase 1/2 1, Phase 1 1) 2018: 26 trials (Observational 7, Not applicable 16, Phase 4 1, Phase 2 1, Phase 1/2 1) 2019: 42 trials (Other 1, Observational 15, Not applicable 23, Phase 2 1, Phase 1/2 2) 2020: 32 trials (Observational 10, Not applicable 16, Phase 1/2 3, Phase 1 3) 2021: 38 trials (Observational 7, Not applicable 24, Phase 2/3 2, Phase 2 4, Phase 1/2 1) 2022: 43 trials (Observational 9, Not applicable 29, Phase 2 3, Phase 1 2) 2023: 39 trials (Observational 10, Not applicable 22, Phase 3 2, Phase 2/3 1, Phase 2 1, Phase 1/2 1, Phase 1 2) 2024: 46 trials (Observational 11, Not applicable 28, Phase 2 2, Phase 1/2 3, Phase 1 2) 2025: 46 trials (Observational 16, Not applicable 28, Phase 1/2 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 30
2025 46
2024 46
2023 39
2022 43
2021 38
2020 32
2019 42
2018 26
2017 19

Forecast of the full-year count, planned starts included, not rows of this table: about 39 trials starting in 2026 and about 44 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 61 trials still running at the 2026-10-09 snapshot; registered median of 16 months across 243 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hearing Loss, Sensorineural trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 16
Phase 1/2 22
Phase 2 22
Phase 2/3 5
Phase 3 12
Phase 4 1
Not applicable 251
Observational 128
Unknown 4

How many Hearing Loss, Sensorineural trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 33
Recruiting 80
Enrolling by invitation 10
Active, not recruiting 17
Completed 217

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hearing Loss, Sensorineural trials? (10)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Cochlear 29
MED-EL Elektromedizinische Geräte GesmbH 18
Sonova AG 18
Med-El Corporation 12
Oticon Medical 11

Which drugs are being tested for Hearing Loss, Sensorineural? (1)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
METHYLPREDNISOLONE 2

Interventions as named in the registry (14)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
FX-322 5
N Acetylcysteine 4
Valganciclovir 3
Low dose zonisamide 3
Sham Procedure 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hearing Loss, Sensorineural trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Loss of residual hearing 21 1
Profound/total loss of residual hearing 8 1
Loss of Residual Hearing 7 1
Total Eye Disorders 5 1
Facial weakness/paresis 3 1

Which publications cover Hearing Loss, Sensorineural? (420)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Hearing of Edentulous Patients With a Single Implant-Retained Removable Complete Overdenture: A Case Series. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 2026 Yes
Relationship Between Working Memory, Compression, and Beamformers in Ideal Conditions. Ear and hearing 2025 Yes
Hyperbaric oxygen therapy and corticosteroids as combined treatment for acute acoustic trauma. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2025 Yes
Laser prophylaxis for retinal detachment in Stickler syndrome: A systematic review and meta-analysis. Acta ophthalmologica 2025 Yes
Paediatric glaucoma in Stickler syndromes: a comprehensive review of prevalence, comorbidities and outcomes. BMJ open ophthalmology 2025 Yes

Sub-conditions in MeSH (4)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages