Skip to content
Pharma Observatory a Scientist.com platform

Condition (MeSH)

Infectious Mononucleosis

ClinicalTrials.gov lists 21 trials for Infectious Mononucleosis or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 5.

MeSH D007244 Infections C01 C15 C20
Email me this page as a PDF

Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 4 Phase 2 Phase 2 2 Phase 2/3 Phase 2/3 1 Observational Observational 11 Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 4 Phase 2 Phase 2 2 Phase 2/3 Phase 2/3 1 Observational Observational 11

Trials per phase

21 of the 21 trials are tagged with Infectious Mononucleosis itself; the rest are tagged with a narrower condition beneath it.

Get the Infectious Mononucleosis report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Infectious Mononucleosis trials start? (14)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Observational

Top of scale: 3

1996: 1 trials (Observational 1) 2002: 1 trials (Observational 1) 2004: 1 trials (Phase 1/2 1) 2007: 1 trials (Phase 1/2 1) 2008: 1 trials (Phase 2/3 1) 2015: 1 trials (Observational 1) 2016: 3 trials (Observational 3) 2017: 1 trials (Observational 1) 2019: 1 trials (Observational 1) 2020: 1 trials (Observational 1) 2021: 2 trials (Observational 1, Phase 1/2 1) 2022: 2 trials (Phase 2 1, Phase 1 1) 2023: 3 trials (Observational 1, Phase 1/2 1, Phase 1 1) 2025: 1 trials (Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 1
2023 3
2022 2
2021 2
2020 1
2019 1
2017 1
2016 3
2015 1
2008 1

No forecast is made for this condition: it averages 1.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Infectious Mononucleosis trials in? (5)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 3
Phase 1/2 4
Phase 2 2
Phase 2/3 1
Observational 11

How many Infectious Mononucleosis trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 4
Active, not recruiting 2
Completed 9
Terminated 2
Withdrawn 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Infectious Mononucleosis trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 5
ModernaTX, Inc. 2
Henogen 1

Which drugs are being tested for Infectious Mononucleosis? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
RITUXIMAB 1
Valomaciclovir 1
Matrix-M1 Adjuvant 1

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
EBV gp350-Ferritin Vaccine 2
mRNA-1189 2
Valacyclovir arrow 1
BrentuximabVedotin (BV) 1
EBV gp350-ferritin vaccine with ALFQ adjuvant 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Infectious Mononucleosis trials report? (4)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Ankle fracture 1 1
Mass 1 1
Pancreatitis 1 1
Testis cancer 1 1

Which publications cover Infectious Mononucleosis? (24)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Overweight/obesity in young adulthood interacts with aspects of EBV infection in MS etiology. Neurology(R) neuroimmunology & neuroinflammation 2021 Yes
Lasting Immunological Imprint of Primary Epstein-Barr Virus Infection With Associations to Chronic Low-Grade Inflammation and Fatigue. Frontiers in immunology 2021 Yes
Environmental factors and risk of multiple sclerosis: Findings from meta-analyses and Mendelian randomization studies. Multiple sclerosis (Houndmills, Basingstoke, England) 2020 Yes
Clinical practice guideline: tonsillitis II. Surgical management. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2016 Yes
Primary immunodeficiencies and the control of Epstein-Barr virus infection. Annals of the New York Academy of Sciences 2015 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages