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Condition (MeSH)

Epstein-Barr Virus Infections

ClinicalTrials.gov lists 1,138 trials for Epstein-Barr Virus Infections or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 117.

MeSH D020031 Infections C01
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Phase 1 Phase 1 367 Phase 1/2 Phase 1/2 152 Phase 2 Phase 2 313 Phase 2/3 Phase 2/3 13 Phase 3 Phase 3 76 Phase 4 Phase 4 9 Not applicable Not applicable 78 Observational Observational 124 Phase 1 Phase 1 367 Phase 1/2 Phase 1/2 152 Phase 2 Phase 2 313 Phase 2/3 Phase 2/3 13 Phase 3 Phase 3 76 Phase 4 Phase 4 9 Not applicable Not applicable 78 Observational Observational 124

Trials per phase (log scale)

2 more sections with rows

167 of the 1,138 trials are tagged with Epstein-Barr Virus Infections itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Epstein-Barr Virus Infections trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access, Unknown)

Top of scale: 56

1990: 4 trials (Not applicable 1, Phase 2 3) 1991: 2 trials (Phase 2 2) 1992: 9 trials (Observational 2, Phase 3 1, Phase 2 5, Phase 1 1) 1993: 5 trials (Observational 1, Phase 2 3, Phase 1 1) 1994: 4 trials (Phase 2 2, Phase 1 2) 1995: 11 trials (Observational 1, Phase 3 2, Phase 2 4, Phase 1/2 1, Phase 1 3) 1996: 15 trials (Observational 4, Phase 2 6, Phase 1 5) 1997: 30 trials (Not applicable 2, Phase 3 6, Phase 2/3 1, Phase 2 9, Phase 1/2 2, Phase 1 10) 1998: 36 trials (Not applicable 1, Phase 4 1, Phase 3 2, Phase 2/3 1, Phase 2 16, Phase 1/2 3, Phase 1 12) 1999: 46 trials (Observational 1, Not applicable 3, Phase 3 6, Phase 2 8, Phase 1/2 5, Phase 1 23) 2000: 48 trials (Observational 2, Not applicable 4, Phase 3 5, Phase 2 18, Phase 1/2 3, Phase 1 16) 2001: 23 trials (Not applicable 3, Phase 3 3, Phase 2 7, Phase 1/2 1, Phase 1 9) 2002: 37 trials (Observational 2, Not applicable 4, Phase 4 1, Phase 3 4, Phase 2 10, Phase 1/2 2, Phase 1 14) 2003: 36 trials (Observational 3, Not applicable 6, Phase 3 2, Phase 2 10, Phase 1/2 6, Phase 1 9) 2004: 46 trials (Observational 1, Not applicable 6, Phase 3 4, Phase 2 15, Phase 1/2 3, Phase 1 17) 2005: 43 trials (Observational 6, Not applicable 4, Phase 3 2, Phase 2 14, Phase 1/2 5, Phase 1 12) 2006: 36 trials (Observational 4, Not applicable 3, Phase 3 3, Phase 2 10, Phase 1/2 3, Phase 1 13) 2007: 42 trials (Other 1, Observational 5, Not applicable 3, Phase 3 4, Phase 2 11, Phase 1/2 5, Phase 1 13) 2008: 36 trials (Observational 8, Not applicable 2, Phase 3 6, Phase 2/3 1, Phase 2 7, Phase 1/2 4, Phase 1 8) 2009: 32 trials (Other 1, Observational 6, Not applicable 2, Phase 3 1, Phase 2 9, Phase 1/2 2, Phase 1 11) 2010: 32 trials (Observational 5, Not applicable 4, Phase 2 13, Phase 1/2 2, Phase 1 8) 2011: 28 trials (Observational 3, Not applicable 2, Phase 3 2, Phase 2 11, Phase 1/2 4, Phase 1 6) 2012: 18 trials (Observational 3, Not applicable 1, Phase 3 2, Phase 2 3, Phase 1/2 4, Phase 1 5) 2013: 28 trials (Observational 3, Phase 2 7, Phase 1/2 4, Phase 1 14) 2014: 30 trials (Not applicable 4, Phase 3 4, Phase 2/3 1, Phase 2 6, Phase 1/2 7, Phase 1 8) 2015: 22 trials (Observational 2, Not applicable 2, Phase 4 1, Phase 3 1, Phase 2 8, Phase 1/2 4, Phase 1 4) 2016: 33 trials (Observational 6, Not applicable 2, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 7, Phase 1/2 5, Phase 1 10) 2017: 36 trials (Observational 4, Phase 3 3, Phase 2 12, Phase 1/2 6, Phase 1 11) 2018: 27 trials (Observational 1, Phase 2 12, Phase 1/2 6, Phase 1 8) 2019: 40 trials (Observational 2, Not applicable 2, Phase 3 5, Phase 2 11, Phase 1/2 7, Phase 1 13) 2020: 27 trials (Observational 5, Phase 2 5, Phase 1/2 4, Phase 1 13) 2021: 39 trials (Observational 6, Phase 4 4, Phase 3 1, Phase 2/3 1, Phase 2 8, Phase 1/2 6, Phase 1 13) 2022: 43 trials (Observational 5, Phase 4 1, Phase 2/3 1, Phase 2 13, Phase 1/2 11, Phase 1 12) 2023: 37 trials (Observational 7, Not applicable 2, Phase 3 1, Phase 2 4, Phase 1/2 8, Phase 1 15) 2024: 35 trials (Observational 10, Not applicable 3, Phase 2/3 1, Phase 2 4, Phase 1/2 7, Phase 1 10) 2025: 56 trials (Observational 5, Not applicable 7, Phase 3 1, Phase 2/3 3, Phase 2 9, Phase 1/2 11, Phase 1 20)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 43
2025 56
2024 35
2023 37
2022 43
2021 39
2020 27
2019 40
2018 27
2017 36

Forecast of the full-year count, planned starts included, not rows of this table: about 52 trials starting in 2026 and about 47 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 118 trials still running at the 2026-10-09 snapshot; registered median of 47 months across 694 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Epstein-Barr Virus Infections trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 367
Phase 1/2 152
Phase 2 313
Phase 2/3 13
Phase 3 76
Phase 4 9
Not applicable 78
Observational 124
Expanded access 5
Unknown 1

How many Epstein-Barr Virus Infections trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 36
Recruiting 153
Enrolling by invitation 3
Active, not recruiting 59
Available 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Epstein-Barr Virus Infections trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 117
Children's Oncology Group 25
National Institutes of Health Clinical Center (CC) 15

Which drugs are being tested for Epstein-Barr Virus Infections? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Cytoxan 213
RITUXIMAB 114
Prednisone 65

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
SQ Fludarabine 115
Etoposid 97
Peripheral blood stem cell transplantation 93
Filgrastime (G-CSF) 89
HD- Methotrexate (MTX) 86

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Epstein-Barr Virus Infections trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Neutrophil count decreased 1,047 30
Platelet count decreased 871 30
Febrile neutropenia 835 62
White blood cell decreased 694 14
Anemia 507 26

Which publications cover Epstein-Barr Virus Infections? (272)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages