Condition (MeSH)
Leptospirosis
ClinicalTrials.gov lists 24 trials for Leptospirosis or a narrower condition beneath it. Institut Pasteur has the most among industry and government lead sponsors, with 3.
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Trials per phase
24 of the 24 trials are tagged with Leptospirosis itself; the rest are tagged with a narrower condition beneath it.
When did Leptospirosis trials start? (14)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 2/3
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 3 |
| 2025 | 5 |
| 2024 | 1 |
| 2022 | 2 |
| 2021 | 3 |
| 2020 | 1 |
| 2019 | 1 |
| 2017 | 2 |
| 2016 | 1 |
| 2014 | 1 |
Showing 10 of 14 earlier years.
No forecast is made for this condition: it averages 1.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Leptospirosis trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 2 |
| Phase 2/3 | 1 |
| Phase 4 | 1 |
| Not applicable | 9 |
| Observational | 11 |
How many Leptospirosis trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 5 |
| Recruiting | 4 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 1 |
| Completed | 8 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Leptospirosis trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Institut Pasteur | 3 |
| Cepheid | 1 |
| Imaxio | 1 |
| Institut National de la Santé Et de la Recherche Médicale, France | 1 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| data collection | 2 |
| N Acetylcysteine | 1 |
| Cohort | 1 |
| Blood collection | 1 |
| Dexamethasone, desmopressin | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Leptospirosis? (50)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Etiological spectrum of persistent fever in the tropics and predictors of ubiquitous infections: a prospective four-country study with pooled analysis. | BMC medicine | 2022 | Yes |
| Clinical evaluation of the BioFire Global Fever Panel for the identification of malaria, leptospirosis, chikungunya, and dengue from whole blood: a prospective, multicentre, cross-sectional diagnostic accuracy study. | The Lancet. Infectious diseases | 2022 | Yes |
| Artificial intelligence in differentiating tropical infections: A step ahead. | PLoS neglected tropical diseases | 2022 | Yes |
| Factors associated with severity and mortality in patients with confirmed leptospirosis at a regional hospital in northern Taiwan. | Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi | 2020 | Yes |
| A simple score to predict severe leptospirosis. | PLoS neglected tropical diseases | 2019 | Yes |
Showing 5 of 50 publications.
Prevalence (81)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Leptospirosis | Annual incidence | 1-9 / 1 000 000 | United Kingdom | GB | Exact |
| Leptospirosis | Annual incidence | 1-9 / 1 000 000 | United Kingdom | GB | Exact |
| Leptospirosis | Annual incidence | 1-9 / 1 000 000 | United Kingdom | GB | Unspecified |
| Leptospirosis | Annual incidence | 1-9 / 1 000 000 | Romania | Not stated | Unspecified |
| Leptospirosis | Annual incidence | 1-9 / 1 000 000 | Slovakia | Not stated | Unspecified |
Showing 5 of 81 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Leptospirosis | 509 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Leptospirosis | 509 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.