Condition (MeSH)
Mandibular Diseases
ClinicalTrials.gov lists 691 trials for Mandibular Diseases or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
5 of the 691 trials are tagged with Mandibular Diseases itself; the rest are tagged with a narrower condition beneath it.
When did Mandibular Diseases trials start? (28)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 79
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 64 |
| 2025 | 79 |
| 2024 | 75 |
| 2023 | 79 |
| 2022 | 57 |
| 2021 | 52 |
| 2020 | 36 |
| 2019 | 43 |
| 2018 | 32 |
| 2017 | 22 |
Showing 10 of 28 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 82 trials starting in 2026 and about 79 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 31 months from start to primary completion across 53 trials still running at the 2026-10-09 snapshot; registered median of 10 months across 415 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Mandibular Diseases trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 15 |
| Phase 1/2 | 9 |
| Phase 2 | 26 |
| Phase 2/3 | 11 |
| Phase 3 | 9 |
| Phase 4 | 14 |
| Not applicable | 418 |
| Observational | 189 |
How many Mandibular Diseases trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 61 |
| Recruiting | 72 |
| Enrolling by invitation | 18 |
| Active, not recruiting | 14 |
| Completed | 390 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| type A botulinum toxin | 13 |
| Low Level Laser Therapy | 11 |
| Acupuncture | 5 |
| [PRP] platelet rich plasma | 5 |
| Physiotherapy | 4 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Mandibular Diseases trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| metabolism | 3 | 1 |
| Abdominal pain upper | 1 | 1 |
| Acute kidney injury | 1 | 1 |
| Alcohol abuse | 1 | 1 |
| Appendicitis | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Mandibular Diseases? (102)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Doxycycline Sclerotherapy of Mandibular Aneurysmal Bone Cysts: A Brief Clinical Study. | The Journal of craniofacial surgery | 2025 | Yes |
| Diagnostic accuracy of CBCT versus intraoral imaging for assessment of peri-implant bone defects. | BMC medical imaging | 2021 | Yes |
| Surgical management of the odontogenic keratocyst: A 20-year experience. | International journal of oral and maxillofacial surgery | 2021 | Yes |
| Endoscopic-assisted enucleation of large mandibular odontogenic cysts. | Oral surgery, oral medicine, oral pathology and oral radiology | 2020 | Yes |
| Computer-Assisted versus Conventional Freehand Mandibular Reconstruction with Fibula Free Flap: A Systematic Review and Meta-Analysis. | Plastic and reconstructive surgery | 2019 | Yes |
Showing 5 of 102 publications.
Sub-conditions in MeSH (4)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: lead sponsors, prevalence, and rare-disease identity.