Condition (MeSH)
Marburg Virus Disease
ClinicalTrials.gov lists 12 trials for Marburg Virus Disease or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 4.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
12 of the 12 trials are tagged with Marburg Virus Disease itself; the rest are tagged with a narrower condition beneath it.
When did Marburg Virus Disease trials start? (11)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 1 |
| 2024 | 1 |
| 2023 | 1 |
| 2021 | 1 |
| 2018 | 2 |
| 2017 | 1 |
| 2013 | 1 |
| 2011 | 1 |
| 2010 | 1 |
Showing 10 of 11 earlier years.
No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Marburg Virus Disease trials in? (2)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 2 |
How many Marburg Virus Disease trials are recruiting? (3)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 1 |
| Active, not recruiting | 1 |
| Completed | 10 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Marburg Virus Disease trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | 4 |
| Sarepta Therapeutics, Inc. | 2 |
| BioCryst Pharmaceuticals | 1 |
| International AIDS Vaccine Initiative | 1 |
| Public Health Vaccines LLC | 1 |
Which drugs are being tested for Marburg Virus Disease? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| PHV01 | 2 |
| AVI-7288 | 1 |
| Galidesivir | 1 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| cAd3-Marburg Vaccine | 3 |
| Ad26 Zaire Ebola Vaccine | 1 |
| VRC-EBODNA023-00-VP | 1 |
| VRC-MARDNA025-00-VP | 1 |
| AVI-6003 | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Marburg Virus Disease trials report? (4)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Abortion spontaneous | 1 | 1 |
| Breast Cancer | 1 | 1 |
| Staphylococcal infection | 1 | 1 |
| gastrooesophageal cancer | 1 | 1 |
Which publications cover Marburg Virus Disease? (8)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Codon-optimized filovirus DNA vaccines delivered by intramuscular electroporation protect cynomolgus macaques from lethal Ebola and Marburg virus challenges. | Human vaccines & immunotherapeutics | 2015 | Yes |
| Ebola virus disease and Marburg disease in pregnancy: a review and management considerations for filovirus infection. | Obstetrics and gynecology | 2015 | Yes |
| AVI-7288 for Marburg Virus in Nonhuman Primates and Humans. | The New England journal of medicine | 2015 | Yes |
| Induction of broad cytotoxic T cells by protective DNA vaccination against Marburg and Ebola. | Molecular therapy : the journal of the American Society of Gene Therapy | 2013 | Yes |
| A multiagent filovirus DNA vaccine delivered by intramuscular electroporation completely protects mice from ebola and Marburg virus challenge. | Human vaccines & immunotherapeutics | 2012 | Yes |
Showing 5 of 8 publications.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Marburg hemorrhagic fever | Cases families | Worldwide | Not stated | Exact | |
| Marburg hemorrhagic fever | Cases families | Worldwide | Not stated | Unspecified | |
| Marburg hemorrhagic fever | Cases families | Worldwide | Not stated | Exact | |
| Marburg hemorrhagic fever | Point prevalence | <1 / 1 000 000 | Worldwide | Not stated | Exact |
| Marburg hemorrhagic fever | Point prevalence | <1 / 1 000 000 | Worldwide | Not stated | Exact |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Marburg hemorrhagic fever | 99826 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Marburg hemorrhagic fever | 99826 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.