Condition (MeSH)
Aggressive Periodontitis
ClinicalTrials.gov lists 56 trials for Aggressive Periodontitis or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
56 of the 56 trials are tagged with Aggressive Periodontitis itself; the rest are tagged with a narrower condition beneath it.
When did Aggressive Periodontitis trials start? (14)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 10
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 2 |
| 2021 | 3 |
| 2020 | 2 |
| 2019 | 1 |
| 2018 | 3 |
| 2017 | 8 |
| 2016 | 5 |
| 2015 | 10 |
| 2014 | 6 |
| 2013 | 3 |
Showing 10 of 14 earlier years.
No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Aggressive Periodontitis trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 3 |
| Phase 2/3 | 4 |
| Phase 3 | 1 |
| Phase 4 | 7 |
| Not applicable | 21 |
| Observational | 20 |
How many Aggressive Periodontitis trials are recruiting? (4)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 3 |
| Completed | 41 |
| Terminated | 1 |
| Unknown status | 11 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which drugs are being tested for Aggressive Periodontitis? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Amoxicillin | 3 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Clarithromycin XL | 4 |
| Metronidazol | 3 |
| open flap debridement | 3 |
| EC Aspirin | 2 |
| fatty acids, omega-3 | 2 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Aggressive Periodontitis trials report? (2)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Internal bleeding | 0 | 1 |
| Stomachache | 0 | 1 |
Which publications cover Aggressive Periodontitis? (99)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Clinical, immunological and microbiological evaluation of experimental peri-implant mucositis and gingivitis in subjects with Grade C, stage III/IV periodontitis background. | Journal of clinical periodontology | 2024 | Yes |
| Treatment of localized aggressive periodontitis alters local host immunoinflammatory profiles: A long-term evaluation. | Journal of clinical periodontology | 2021 | Yes |
| Adjunctive systemic antimicrobials for the non-surgical treatment of periodontitis. | The Cochrane database of systematic reviews | 2020 | Yes |
| Efficacy of regenerative therapy in aggressive periodontitis: a systematic review and meta-analysis of randomised controlled clinical trials. | Clinical oral investigations | 2020 | Yes |
| Moxifloxacin versus amoxicillin plus metronidazole as adjunctive therapy for generalized aggressive periodontitis: a pilot randomized controlled clinical trial. | Quintessence international (Berlin, Germany : 1985) | 2020 | Yes |
Showing 5 of 99 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.