Condition (MeSH)
Pierre Robin Syndrome
ClinicalTrials.gov lists 16 trials for Pierre Robin Syndrome or a narrower condition beneath it. Copka Sonpashan has the most among industry and government lead sponsors, with 1.
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Trials per phase
16 of the 16 trials are tagged with Pierre Robin Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Pierre Robin Syndrome trials start? (12)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2024 | 2 |
| 2023 | 1 |
| 2022 | 2 |
| 2021 | 1 |
| 2019 | 1 |
| 2018 | 1 |
| 2016 | 2 |
| 2015 | 1 |
| 2013 | 1 |
Showing 10 of 12 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Pierre Robin Syndrome trials in? (2)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Not applicable | 8 |
| Observational | 8 |
How many Pierre Robin Syndrome trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Active, not recruiting | 1 |
| Completed | 10 |
| Terminated | 2 |
| Withdrawn | 1 |
| Unknown status | 2 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Pierre Robin Syndrome trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Copka Sonpashan | 1 |
Interventions as named in the registry (1)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| systematic therapy | 2 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Pierre Robin Syndrome? (26)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome. | Nature communications | 2017 | Yes |
| Identification of STAC3 variants in non-Native American families with overlapping features of Carey-Fineman-Ziter syndrome and Moebius syndrome. | American journal of medical genetics. Part A | 2017 | Yes |
| Multicenter study on the effectiveness of the pre-epiglottic baton plate for airway obstruction and feeding problems in Robin sequence. | Orphanet journal of rare diseases | 2017 | Yes |
| Airway management in pierre robin sequence: patterns of practice. | The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association | 2014 | Yes |
| Tracheostomy versus mandibular distraction osteogenesis in infants with Robin sequence: a comparative cost analysis. | The British journal of oral & maxillofacial surgery | 2014 | Yes |
Showing 5 of 26 publications.
Prevalence (45)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Isolated Pierre Robin sequence | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Exact |
| Isolated Pierre Robin sequence | Prevalence at birth | 1-9 / 100 000 | United Kingdom | GB | Unspecified |
| Isolated Pierre Robin sequence | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Unspecified |
| Isolated Pierre Robin sequence | Prevalence at birth | 1-9 / 100 000 | United Kingdom | GB | Exact |
| Isolated Pierre Robin sequence | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Exact |
Showing 5 of 45 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Isolated Pierre Robin sequence | 718 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Isolated Pierre Robin sequence | 718 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.