Condition (MeSH)
Pseudomonas Infections
ClinicalTrials.gov lists 136 trials for Pseudomonas Infections or a narrower condition beneath it. Gilead Sciences has the most among industry and government lead sponsors, with 11.
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Trials per phase (log scale)
1 more section with rows
136 of the 136 trials are tagged with Pseudomonas Infections itself; the rest are tagged with a narrower condition beneath it.
When did Pseudomonas Infections trials start? (26)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 13
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 6 |
| 2025 | 5 |
| 2024 | 9 |
| 2023 | 9 |
| 2022 | 9 |
| 2021 | 5 |
| 2020 | 2 |
| 2019 | 2 |
| 2018 | 6 |
| 2017 | 5 |
Showing 10 of 26 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 5 trials starting in 2026 and about 5 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. The 2026 forecast is below the 6 already registered with a 2026 start date: at the cutoff, 2 trials were already registered to start in October to December, more than the method's monthly average allows for, and the method does not use those planned starts.
Prediction, not a registry value: median of 30 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 24 months across 88 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Pseudomonas Infections trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 8 |
| Phase 1/2 | 12 |
| Phase 2 | 25 |
| Phase 2/3 | 1 |
| Phase 3 | 18 |
| Phase 4 | 18 |
| Not applicable | 12 |
| Observational | 39 |
| Expanded access | 3 |
How many Pseudomonas Infections trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 5 |
| Recruiting | 14 |
| Active, not recruiting | 2 |
| Completed | 78 |
| Approved for marketing | 2 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Pseudomonas Infections trials? (11)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Gilead Sciences | 11 |
| Novartis Pharmaceuticals | 4 |
| Humanigen, Inc. | 3 |
| National Heart, Lung, and Blood Institute (NHLBI) | 3 |
| Aradigm Corporation | 2 |
Showing 5 of 11 sponsors.
Which drugs are being tested for Pseudomonas Infections? (4)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Ceftazidime | 4 |
| POL7080 | 2 |
| Amikacin | 2 |
| Colomycin | 2 |
Interventions as named in the registry (11)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| tobramycin / TOBI | 7 |
| PO ciprofloxacin | 4 |
| 1% Azithromycin | 3 |
| Ceftolozane-Tazobactam | 3 |
| Tobramycin Inhalation Powder | 3 |
Showing 5 of 11 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Pseudomonas Infections trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Cough | 182 | 8 |
| Dyspnoea | 93 | 7 |
| Infective pulmonary exacerbation of cystic fibrosis | 73 | 4 |
| Productive cough | 73 | 4 |
| Pulmonary function test decreased | 53 | 8 |
Showing 5 of 10 adverse events.
Which publications cover Pseudomonas Infections? (393)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Clinical and Lung Microbiome Impact of Chronic Versus Intermittent Pseudomonas aeruginosa Infection in Bronchiectasis. | Archivos de bronconeumologia | 2025 | Yes |
| Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis. | Nature medicine | 2025 | Yes |
| Pseudomonas aeruginosa carriage and associated risk factors in healthy individuals and patients from Rotterdam, Rome, and Jakarta. | Scientific reports | 2025 | Yes |
| ALPINE2: Efficacy and safety of 14-day vs 28-day inhaled aztreonam for Pa eradication in children with cystic fibrosis. | Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society | 2024 | Yes |
| Eradication treatment for <i>Pseudomonas aeruginosa</i> infection in adults with bronchiectasis: a systematic review and meta-analysis. | European respiratory review : an official journal of the European Respiratory Society | 2024 | Yes |
Showing 5 of 393 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.