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Condition (MeSH)

Q Fever

ClinicalTrials.gov lists 12 trials for Q Fever or a narrower condition beneath it. U.S. Army Medical Research and Development Command has the most among industry and government lead sponsors, with 2.

MeSH D011778 Infections C01 Listed by Orphanet as a rare disease
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Phase 2 Phase 2 2 Phase 4 Phase 4 1 Not applicable Not applicable 3 Observational Observational 6 Phase 2 Phase 2 2 Phase 4 Phase 4 1 Not applicable Not applicable 3 Observational Observational 6

Trials per phase

12 of the 12 trials are tagged with Q Fever itself; the rest are tagged with a narrower condition beneath it.

Get the Q Fever report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Q Fever trials start? (9)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 2
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 2

2006: 2 trials (Phase 2 2) 2009: 1 trials (Observational 1) 2010: 1 trials (Not applicable 1) 2011: 2 trials (Observational 1, Phase 4 1) 2013: 1 trials (Not applicable 1) 2014: 1 trials (Observational 1) 2017: 1 trials (Observational 1) 2025: 2 trials (Observational 1, Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 2
2017 1
2014 1
2013 1
2011 2
2010 1
2009 1
2006 2

No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 12 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Q Fever trials in? (4)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 2 2
Phase 4 1
Not applicable 3
Observational 6

How many Q Fever trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 2
Recruiting 1
Completed 4
Withdrawn 1
Unknown status 4

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Q Fever trials? (1)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
U.S. Army Medical Research and Development Command 2

Interventions as named in the registry (5)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Q Fever Vaccine (NDBR 105 1
Blood Test 1
Q fever Vaccine 1
Doxycline 1
Blood Sampling 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Q Fever trials report? (5)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Cardiological symptoms 1 1
Chills 1 1
Malaise 1 1
Paraesthesia 1 1
Urosepsis 1 1

Which publications cover Q Fever? (28)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Coxiella burnetii-Infected NK Cells Release Infectious Bacteria by Degranulation. Infection and immunity 2020 Yes
Effectiveness of Long-term Doxycycline Treatment and Cognitive-Behavioral Therapy on Fatigue Severity in Patients with Q Fever Fatigue Syndrome (Qure Study): A Randomized Controlled Trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Yes
Seroprevalence of rickettsial infections and Q fever in Bhutan. PLoS neglected tropical diseases 2017 Yes
Undifferentiated febrile illness in Kathmandu, Nepal. The American journal of tropical medicine and hygiene 2015 Yes
Atypical pneumonia. Current opinion in pulmonary medicine 2014 Yes

Prevalence (72)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Q fever Annual incidence 1-9 / 1 000 000 United Kingdom GB Unspecified
Q fever Annual incidence 1-9 / 1 000 000 United Kingdom GB Exact
Q fever Annual incidence 1-9 / 1 000 000 United Kingdom GB Exact
Q fever Annual incidence <1 / 1 000 000 United States US Exact
Q fever Annual incidence <1 / 1 000 000 United States US Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Q fever 781 Exact Orphanet Rare Disease Ontology (ORDO)
Q fever 781 Exact Orphadata Science knowledge files, Product 1

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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