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Condition (MeSH)

Cumulative Trauma Disorders

ClinicalTrials.gov lists 663 trials for Cumulative Trauma Disorders or a narrower condition beneath it.

MeSH D012090 Wounds and Injuries C26
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Phase 1 Phase 1 13 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 21 Phase 2/3 Phase 2/3 6 Phase 3 Phase 3 11 Phase 4 Phase 4 42 Not applicable Not applicable 412 Observational Observational 150 Phase 1 Phase 1 13 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 21 Phase 2/3 Phase 2/3 6 Phase 3 Phase 3 11 Phase 4 Phase 4 42 Not applicable Not applicable 412 Observational Observational 150

Trials per phase (log scale)

40 of the 663 trials are tagged with Cumulative Trauma Disorders itself; the rest are tagged with a narrower condition beneath it.

Get the Cumulative Trauma Disorders report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Cumulative Trauma Disorders trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 77

1997: 1 trials (Not applicable 1) 1999: 1 trials (Phase 2 1) 2002: 3 trials (Observational 2, Not applicable 1) 2003: 5 trials (Observational 2, Not applicable 1, Phase 4 1, Phase 3 1) 2004: 4 trials (Observational 1, Not applicable 1, Phase 4 2) 2005: 2 trials (Not applicable 1, Phase 3 1) 2006: 7 trials (Observational 1, Not applicable 2, Phase 3 1, Phase 2 2, Phase 1/2 1) 2007: 9 trials (Observational 1, Not applicable 5, Phase 1/2 3) 2008: 7 trials (Observational 1, Not applicable 3, Phase 2/3 1, Phase 2 1, Phase 1/2 1) 2009: 12 trials (Observational 2, Not applicable 6, Phase 4 1, Phase 3 1, Phase 2 1, Phase 1 1) 2010: 11 trials (Observational 3, Not applicable 5, Phase 3 1, Phase 2 2) 2011: 9 trials (Observational 3, Not applicable 3, Phase 3 2, Phase 1 1) 2012: 11 trials (Observational 2, Not applicable 5, Phase 4 2, Phase 2 2) 2013: 22 trials (Observational 3, Not applicable 12, Phase 4 4, Phase 2 2, Phase 1 1) 2014: 19 trials (Observational 6, Not applicable 11, Phase 4 1, Phase 2 1) 2015: 20 trials (Observational 4, Not applicable 14, Phase 4 1, Phase 2/3 1) 2016: 33 trials (Observational 10, Not applicable 15, Phase 4 2, Phase 2/3 1, Phase 2 2, Phase 1/2 1, Phase 1 2) 2017: 18 trials (Observational 2, Not applicable 13, Phase 4 1, Phase 2 1, Phase 1 1) 2018: 28 trials (Observational 1, Not applicable 20, Phase 4 3, Phase 3 1, Phase 1 3) 2019: 35 trials (Observational 8, Not applicable 22, Phase 4 3, Phase 1/2 1, Phase 1 1) 2020: 38 trials (Observational 9, Not applicable 21, Phase 4 5, Phase 3 1, Phase 2/3 1, Phase 1/2 1) 2021: 53 trials (Observational 14, Not applicable 37, Phase 4 2) 2022: 65 trials (Observational 10, Not applicable 47, Phase 4 5, Phase 2 2, Phase 1 1) 2023: 77 trials (Observational 23, Not applicable 48, Phase 4 3, Phase 3 1, Phase 2/3 2) 2024: 55 trials (Observational 15, Not applicable 40) 2025: 63 trials (Observational 13, Not applicable 42, Phase 4 5, Phase 2 2, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 52
2025 63
2024 55
2023 77
2022 65
2021 53
2020 38
2019 35
2018 28
2017 18

Forecast of the full-year count, planned starts included, not rows of this table: about 66 trials starting in 2026 and about 63 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 34 months from start to primary completion across 52 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 411 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Cumulative Trauma Disorders trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 13
Phase 1/2 8
Phase 2 21
Phase 2/3 6
Phase 3 11
Phase 4 42
Not applicable 412
Observational 150

How many Cumulative Trauma Disorders trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 52
Recruiting 58
Enrolling by invitation 9
Active, not recruiting 16
Completed 386

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Cumulative Trauma Disorders? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
METHYLPREDNISOLONE 7
Corticosteroid 5
Ibuprofen Arginine 4

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
[PRP] platelet rich plasma 10
L:Lidocaine 9
Exercise 8
Triamcinolone Acetonide alone 6
Gabapentin 6% 6

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Cumulative Trauma Disorders trials report? (5)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Other 3 1
Arthritis 2 1
Fracture 1 1
Myocardial infarction 1 1
Nerve Injury - Digital-Median 1 1

Which publications cover Cumulative Trauma Disorders? (226)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
An osteopathic assessment of lower extremity somatic dysfunctions in runners. Journal of osteopathic medicine 2025 Yes
Efficacy of a Rhythmic Gymnastics-Specific Injury Prevention Program: An Assessor-Blinded Cluster-Randomized Controlled Trial. Scandinavian journal of medicine & science in sports 2025 Yes
Turkısh translatıon and valıdatıon of the Oslo Sports Trauma Research Center (OSTRC) Questıonnaıres. Malawi medical journal : the journal of Medical Association of Malawi 2025 Yes
Knee, Low Back, and Shoulder Problems Among University and Professional Volleyball Players: Playing With Pain. Journal of athletic training 2024 Yes
Developing the Singapore youth shoulder overuse injury prevention program. Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine 2024 Yes

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, and rare-disease identity.

Browse all condition evidence pages