Condition (MeSH)
Syphilis, Congenital
ClinicalTrials.gov lists 10 trials for Syphilis, Congenital or a narrower condition beneath it.
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Trials per phase
10 of the 10 trials are tagged with Syphilis, Congenital itself; the rest are tagged with a narrower condition beneath it.
When did Syphilis, Congenital trials start? (5)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 3 |
| 2025 | 2 |
| 2022 | 1 |
| 2019 | 3 |
| 2016 | 1 |
No forecast is made for this condition: it averages 1.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Syphilis, Congenital trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 2 |
| Phase 4 | 1 |
| Not applicable | 3 |
| Observational | 4 |
How many Syphilis, Congenital trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 2 |
| Completed | 3 |
| Withdrawn | 1 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which drugs are being tested for Syphilis, Congenital? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Amoxicillin | 2 |
| Benzathine Penicillin G | 2 |
Interventions as named in the registry (2)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Benzathine penicillin 2.4 million units | 1 |
| Zyvox - linezolid | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Syphilis, Congenital? (17)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Gaps in the Care of Maternal and Congenital Syphilis in Hawai'i, 2022-2023. | The Pediatric infectious disease journal | 2025 | Yes |
| Syphilis in pregnant women and congenital syphilis from 2012 to 2021 in Switzerland: a multicentre, retrospective study. | Swiss medical weekly | 2024 | Yes |
| Congenital syphilis in the twenty-first century: an area-based study. | European journal of pediatrics | 2023 | Yes |
| Advantages and limitations of current diagnostic laboratory approaches in syphilis and congenital syphilis. | Expert review of anti-infective therapy | 2023 | Yes |
| Congenital syphilis prevention in the context of methamphetamine use and homelessness. | The American journal on addictions | 2022 | Yes |
Showing 5 of 17 publications.
Prevalence (51)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Congenital syphilis | Point prevalence | 1-5 / 10 000 | United States | US | Unspecified |
| Congenital syphilis | Prevalence at birth | 1-5 / 10 000 | United States | US | Unspecified |
| Congenital syphilis | Prevalence at birth | 1-5 / 10 000 | United States | US | Exact |
| Congenital syphilis | Point prevalence | 1-5 / 10 000 | United States | US | Exact |
| Congenital syphilis | Point prevalence | 1-5 / 10 000 | United States | US | Exact |
Showing 5 of 51 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Congenital syphilis | 499009 | Exact | Orphadata Science knowledge files, Product 1 |
| Congenital syphilis | 499009 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: lead sponsors, serious adverse events in this condition's trials, and sub-conditions in mesh.